Reversible posterior leukoencephalopathy syndrome in a patient with thrombotic thrombocytopenic purpura

被引:0
|
作者
Paolo Aridon
Paolo Ragonese
Maria Antonietta Mazzola
Gerlando Quintini
Marianna Lo Re
Simona Talamanca
Valeria Terruso
Marco D’Amelio
Giovanni Savettieri
机构
[1] University of Palermo,Biomedicina Sperimentale e Neuroscienze Cliniche (BIONEC)
[2] U.O. di Ematologia,undefined
[3] Azienda Ospedaliera Universitaria Policlinico Paolo Giaccone dell’Università degli Studi di Palermo,undefined
来源
Neurological Sciences | 2011年 / 32卷
关键词
Reversible posterior leukoencephalopathy; Thrombotic thrombocytopenic purpura; ADAMTS-13; Plasma exchange;
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学科分类号
摘要
Thrombotic thrombocytopenic purpura (TTP) is an autoimmune disorder characterised by fever, microangiopathic haemolytic anaemia, renal insufficiency, and thrombocytopenia. Neurological involvement, a prominent component of TTP, is characterised by a variety of brain lesions which include reversible cerebral oedema or magnetic resonance imaging (MRI) features of reversible posterior leukoencephalopathy syndrome (RPLS). TTP is frequently associated with deficiency of the von Willebrand factor-cleaving protease, ADAMTS13.
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页码:469 / 472
页数:3
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