Tanshinone IIA inhibits proliferation and migration by downregulation of the PI3K/Akt pathway in small cell lung cancer cells

[11] Sun A(2020)Pharmacological activity and mechanism of Tanshinone IIA in Related diseases Drug Des Devel Ther 14 4735-57

[12] Durocher-Allen LD(2021)Mechanisms of small cell lung cancer metastasis EMBO Mol Med 13 e13122-74

[13] Ellis PM(2017)Molecular insights into tumour metastasis: tracing the dominant events J Pathol 241 567-23

[14] Ung YC(2021)Progression and metastasis of small cell lung carcinoma: the role of the PI3K/Akt/mTOR pathway and metabolic alterations Cancer Metastasis Rev 40 1141-93

[15] Goffin JR(2008)Selective inhibition of SCLC growth by the A12 anti-IGF-1R monoclonal antibody correlates with inhibition of Akt Lung Cancer 60 166-26

[16] Ramchandar K(2021)Tanshinone IIA affects the malignant growth of Cholangiocarcinoma cells by inhibiting the PI3K-Akt-mTOR pathway Sci Rep 11 19268-93

[17] Darling G(2020)Combination of tanshinone IIA and astragaloside IV attenuate atherosclerotic plaque vulnerability in ApoE(-/-) mice by activating PI3K/AKT signaling and suppressing TRL4/NF-kappaB signaling Biomed Pharmacother 123 109729-48

[18] Gazdar AF(2021)Tanshinone IIA alleviates acute ethanol-induced myocardial apoptosis mainly through inhibiting the expression of PDCD4 and activating the PI3K/Akt pathway Phytother Res 35 4309-35

[19] Bunn PA(2020)Oridonin inhibits the migration and epithelial-to-mesenchymal transition of small cell lung cancer cells by suppressing FAK-ERK1/2 signalling pathway J Cell Mol Med 24 4480-6

[20] Minna JD(2022)Tanshinone IIA inhibits cardiomyocyte apoptosis and rescues cardiac function during doxorubicin-induced cardiotoxicity by activating the DAXX/MEK/ERK1/2 pathway Phytomedicine 107 154471-71

[11] Sun A(2020)Pharmacological activity and mechanism of Tanshinone IIA in Related diseases Drug Des Devel Ther 14 4735-57

[12] Durocher-Allen LD(2021)Mechanisms of small cell lung cancer metastasis EMBO Mol Med 13 e13122-74

[13] Ellis PM(2017)Molecular insights into tumour metastasis: tracing the dominant events J Pathol 241 567-23

[14] Ung YC(2021)Progression and metastasis of small cell lung carcinoma: the role of the PI3K/Akt/mTOR pathway and metabolic alterations Cancer Metastasis Rev 40 1141-93

[15] Goffin JR(2008)Selective inhibition of SCLC growth by the A12 anti-IGF-1R monoclonal antibody correlates with inhibition of Akt Lung Cancer 60 166-26

[16] Ramchandar K(2021)Tanshinone IIA affects the malignant growth of Cholangiocarcinoma cells by inhibiting the PI3K-Akt-mTOR pathway Sci Rep 11 19268-93

[17] Darling G(2020)Combination of tanshinone IIA and astragaloside IV attenuate atherosclerotic plaque vulnerability in ApoE(-/-) mice by activating PI3K/AKT signaling and suppressing TRL4/NF-kappaB signaling Biomed Pharmacother 123 109729-48

[18] Gazdar AF(2021)Tanshinone IIA alleviates acute ethanol-induced myocardial apoptosis mainly through inhibiting the expression of PDCD4 and activating the PI3K/Akt pathway Phytother Res 35 4309-35

[19] Bunn PA(2020)Oridonin inhibits the migration and epithelial-to-mesenchymal transition of small cell lung cancer cells by suppressing FAK-ERK1/2 signalling pathway J Cell Mol Med 24 4480-6

[20] Minna JD(2022)Tanshinone IIA inhibits cardiomyocyte apoptosis and rescues cardiac function during doxorubicin-induced cardiotoxicity by activating the DAXX/MEK/ERK1/2 pathway Phytomedicine 107 154471-71