Biomarkers of acute kidney injury in pediatric cardiac surgery

被引：0
作者：
Candice Torres de Melo Bezerra Cavalcante
Marcelo Borges Cavalcante
Klebia Magalhães Pereira Castello Branco
Titus Chan
Isabel Cristina Leite Maia
Ronald Guedes Pompeu
Andrea Consuelo de Oliveira Telles
Anna Karina Martins Brito
Alexandre Braga Libório
机构：
[1] Pediatric Cardiac Center of the Messejana Hospital Dr. Carlos Alberto Studart Gomes,Department of Pediatrics
[2] Fortaleza University (UNIFOR),Department of Obstetrics and Gynecology
[3] Fortaleza University (UNIFOR),The Heart Center, Seattle Children’s Hospital
[4] University of Washington,Medical Sciences Postgraduate Program
[5] Fortaleza University (UNIFOR),undefined
来源：
Pediatric Nephrology | 2022年 / 37卷
关键词：
Acute Kidney Injury; Biomarkers; Cardiac surgery; Children;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Acute kidney injury (AKI) is characterized by a sudden decrease in kidney function. Children with congenital heart disease are a special group at risk of developing AKI. We performed a systematic review of the literature to search for studies reporting the usefulness of novel urine, serum, and plasma biomarkers in the diagnosis and progression of AKI and their association with clinical outcomes in children undergoing pediatric cardiac surgery. In thirty studies, we analyzed the capacity to predict AKI and poor outcomes of five biomarkers: Cystatin C, Neutrophil gelatinase-associated lipocalin, Interleukin-18, Kidney injury molecule-1, and Liver fatty acid–binding protein. In conclusion, we suggest the need for further meta-analyses with the availability of additional studies.
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页码：61 / 78
页数：17
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