Gentamicin promoted the production of CD4+CD25+ Tregs via the STAT5 signaling pathway in mice sepsis

被引:0
作者
Jinfeng Li
Fengdan Xu
Song Li
Mingyu Xie
Ning Li
机构
[1] Guangdong Medical University Affiliated Dongguan Children’s Hospital,Department of Neonatology
来源
BMC Immunology | / 23卷
关键词
Neonatal sepsis; Regulatory T cell; Gentamicin; STAT5; Inflammation;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 281 条
[1]  
Kim F(2020)Neonatal sepsis BMJ 371 m3672-452
[2]  
Polin RA(2020)Neonatal sepsis in low-income countries: epidemiology, diagnosis and prevention Expert Rev Anti-Infect Ther 18 443-440
[3]  
Hooven TA(2015)Global, regional, and national causes of child mortality in 2000–13, with projections to inform post-2015 priorities: an updated systematic analysis Lancet 385 430-e760
[4]  
Popescu CR(2016)Characterisation and antimicrobial resistance of sepsis pathogens in neonates born in tertiary care centres in Delhi, India: a cohort study Lancet Glob Health 4 e752-278
[5]  
Cavanagh MMM(2018)Adjuvant pretreatment with alum protects neonatal mice in sepsis through myeloid cell activation Clin Exp Immunol 191 268-233
[6]  
Tembo B(2014)The new normal: immunomodulatory agents against sepsis immune suppression Trends Mol Med 20 224-309
[7]  
Chiume M(2016)Development and maintenance of intestinal regulatory T cells Nat Rev Immunol 16 295-344
[8]  
Lufesi N(2020)Maresin1 ameliorates acute lung injury induced by sepsis through regulating Th17/Treg balance Life Sci 254 117773-176
[9]  
Goldfarb DM(2020)Baicalin suppresses Th1 and Th17 responses and promotes Treg response to ameliorate sepsis-associated pancreatic injury via the RhoA-ROCK pathway Int Immunopharmacol 86 106685-3668
[10]  
Kissoon N(2013)Increased proportion of CD4(+)CD25(+)Foxp3(+) regulatory T cells during early-stage sepsis in ICU patients J Microbiol Immunol Infect 46 338-290