Factor V G1691A, Prothrombin G20210A, and Methylenetetrahydrofolate Reductase [MTHFR] C677T Gene Polymorphism in Angiographically Documented Coronary Artery Disease

被引：0
作者：
Wassim Y. Almawi
Ghada Ameen
Hala Tamim
Ramzi R. Finan
Noha Irani-Hakime
机构：
[1] Arabian Gulf University,Department of Medicine
[2] American University of Beirut,Department of Epidemiology and Biostatistics
[3] St. Georges-Orthodox Hospital,Department of Obstetrics and Gynecology
来源：
Journal of Thrombosis and Thrombolysis | 2004年 / 17卷
关键词：
coronary artery disease; MTHFR; mutations; coagulation factors;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background: Single point mutations in the genes coding for factor V [G1691A; Leiden], prothrombin [PRT; G20210A], and methylenetetrahydrofolate reductase [MTHFR, C677T] were shown to be major inherited predisposing factors for venous thromboembolism. However, their contribution in the development of coronary artery disease [CAD] remains controversial. The aim of the study was to examine the association of these mutations in CAD.
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页码：199 / 205
页数：6
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