Calcium-phosphorus homeostasis in cats with spontaneous chronic kidney disease and metabolic acidosis

被引：0
作者：
Rosama Pusoonthornthum
Onrassamee Vimuktanandana
Pinit Pusoonthornthum
Anudep Rungsipipat
Nateetip Krishnamra
机构：
[1] Department of Veterinary Medicine, Faculty of Veterinary Science, Chulalongkorn University
[2] Department of Veterinary Pathology, Faculty of Veterinary Science, Chulalongkorn University
[3] Department of Physiology, Faculty of Science, Mahidol University
来源：
Comparative Clinical Pathology | 2012年 / 21卷 / 5期
关键词：
Cats; Chronic kidney disease; Metabolic acidosis;
D O I：
10.1007/s00580-011-1213-8
中图分类号：
学科分类号：
摘要：
The effect of metabolic acidosis on calcium-phosphorus homeostasis in cats with spontaneous chronic kidney disease (CKD) was studied. The cats were assigned into the clinically normal cats (n = 6), CKD (n = 9), and CKD with metabolic acidosis (12 cats). The CKD cats were cats with a blood urea nitrogen ≥50 mg/dl and creatinine level ≥2. 1 mg/dl. A complete blood count, sodium, potassium, total calcium, adjusted calcium, ionized calcium, phosphorus, parathyroid hormone, and vitamin D levels were measured. The cats with spontaneous CKD had a significantly lower hemoglobin and pack cell volume than the clinically normal cats. The CKD cats with metabolic acidosis had mean creatinine levels of 7. 12 ± 0. 76 mg/dl (severe azotemic stage) and significantly increased levels of parathyroid hormone and plasma phosphorus levels which indicated the presence of renal secondary hyperparathyroidism. © 2011 Springer-Verlag London Limited.
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页码：985 / 991
页数：6
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