Asthma and Indoor Environment: Usefulness of a Global Allergen Avoidance Method on Asthma Control and Exposure to Molds

被引：0

作者：

Jean-Pierre Gangneux

Matthieu Bouvrais

Sophie Frain

Hugues Morel

Séverine Deguen

Sylviane Chevrier

Pierre Le Cann

机构：

[1] Univ Rennes,Irset (Institut de Recherche en santé, environnement et travail) – UMR_S 1085

[2] CHU Rennes,Département de Médecine Générale

[3] Inserm,Service de Pneumologie

[4] EHESP,Service de Parasitologie

[5] Université de Rennes 1,Mycologie

[6] Association Capt’air Bretagne,undefined

[7] Centre Hospitalier d’Orléans,undefined

[8] EHESP,undefined

[9] Inserm,undefined

[10] Irset (Institut de Recherche en santé,undefined

[11] environnement et travail) – UMR_S 1085,undefined

[12] Centre Hospitalier Universitaire de Rennes,undefined

来源：

Mycopathologia | 2020年 / 185卷

关键词：

Home intervention; Asthma; Allergens; Pollutants; Molds;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

The usefulness and feasibility of a global allergens avoidance method with counselors visiting patients’ home for allergens measures and adapted advices were prospectively evaluated through asthma control and environment evaluation. Twenty seven patients were prospectively included and compared to a cohort of 30 control patients. The level of control of asthma at inclusion and after 1 year was evaluated by the clinical signs, the evolution of the FEV1, and the healthcare use. Environmental measurements included the fungal load of 5 surfaces of the dwellings and the evaluation of moisture. A significant clinical improvement in the population that benefited from the home counselors visit was observed compared to the baseline (p < 0.0001), as well as a decreased number of hospitalizations for asthma and of the consumption of anti-asthma drugs (p < 0.01). Dampness markers slightly improved with an improvement of the fungal loads in two-third of the dwellings.

引用

页码：367 / 371

页数：4

共 58 条

[1]

Beasley R(2015)Risk factors for asthma: is prevention possible? Lancet 386 1075-1085

[2]

Semprini A(2007)Asthma cases attributable to atopy: results from the Third National Health and Nutrition Examination Survey J Allergy Clin Immunol 120 1139-1145

[3]

Mitchell EA(2017)Home environmental interventions for the prevention or control of allergic and respiratory diseases: What Really Works J Allergy Clin Immun Pract 5 66-79

[4]

Arbes SJ(2004)Results of a home-based environmental intervention among urban children with asthma New Engl J Med 351 1068-1080

[5]

Gergen PJ(2006)The link between fungi and severe asthma: a summary of the evidence Eur Resp J 27 615-626

[6]

Vaughn B(2017)Association of household cleaning agents and disinfectants with asthma in young German adults Occup Environ Med 74 684-690

[7]

Zeldin DC(2018)Cleaning at home and at work in relation to lung function decline and airway obstruction Am J Respir Crit Care Med 197 1157-1163

[8]

Le Cann P(2015)Indoor environmental exposures and exacerbation of asthma: an update to the 2000 review by the Institute of Medicine Envir Health Perspect 123 6-122

[9]

Paulus H(2017)Microbes, allergic sensitization, and the natural history of asthma Curr Opin Allergy Clin Immunol 17 116-134

[10]

Glorennec P(2014)Current asthma in schoolchildren is related to fungal spores in classrooms Chest 146 123-340

← 1 2 3 4 5 6 →