Bi-stable neural state switches

被引：0
|
作者：
André Berndt
Ofer Yizhar
Lisa A Gunaydin
Peter Hegemann
Karl Deisseroth
机构：
[1] Institute of Biology,Department of Bioengineering
[2] Experimental Biophysics,Department of Psychiatry and Behavioral Sciences
[3] Humboldt-University,undefined
[4] Behavioral Sciences,undefined
[5] W083 Clark Center,undefined
[6] 318 Campus Drive West,undefined
[7] Stanford University,undefined
[8] Neuroscience Program,undefined
[9] Behavioral Sciences,undefined
[10] W083 Clark Center,undefined
[11] W083 Clark Center,undefined
来源：
Nature Neuroscience | 2009年 / 12卷
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学科分类号：
摘要：
Transgenic expression of microbial channelrhodopsins in neurons allows direct light activation of ionic currents. Here, the authors describe a modified channelrhodopsin that remains open for seconds once it is activated by light and can be 'switched off' by a second light flash, thereby obviating the need for constant illumination during an experiment.
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页码：229 / 234
页数：5
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