The Role of Histone Modifications and Variants in Regulating Gene Expression in Breast Cancer

被引：0
|
作者：
Mathieu Dalvai
Kerstin Bystricky
机构：
[1] Université de Toulouse,
[2] LBME,undefined
[3] CNRS,undefined
来源：
Journal of Mammary Gland Biology and Neoplasia | 2010年 / 15卷
关键词：
Breast cancer; Estrogen; Epigenetics; Methylation; Acetylation; Histone variants;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The role of epigenetic phenomena in cancer biology is increasingly being recognized. Here we focus on the mechanisms and enzymes involved in regulating histone methylation and acetylation, and the modulation of histone variant expression and deposition. Implications of these epigenetic marks for tumor development, progression and invasiveness are discussed with a particular emphasis on breast cancer progression.
引用
收藏
页码：19 / 33
页数：14
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