Synthesis and biological evaluation of chalcones and acetyl pyrazoline derivatives comprising furan nucleus as an antitubercular agents

被引：0
作者：
Dinesh Bhoot
Ranjan C. Khunt
Hansa H. Parekh
机构：
[1] Saurashtra University,Chemical Research Laboratory, Department of Chemistry
来源：
Medicinal Chemistry Research | 2012年 / 21卷
关键词：
Chalcones; Pyrazoles; Antimicrobial activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
A series of 1-{5-[5-(m,p-dichlorophenyl)furan-2-yl]-3-aryl-4,5-dihydro-1H-pyrazol-1-yl} ethanone (3a–k) have been synthesized by the condensation of (2E)-3-[5-(m,p-dichlorophenyl)furan-2-yl]-1-arylprop-2-en-1-one (2a–k) with hydrazine hydrate in glacial acetic acid. The synthesized compounds have been characterized on the basis of elemental analyses and spectral studies. All the synthesized products have been screened for their antibacterial, antifungal, and antitubercular activity.
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页码：3233 / 3239
页数：6
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