DNA methylation analysis reveals distinct methylation signatures in pediatric germ cell tumors

被引:0
作者
James F Amatruda
Julie A Ross
Brock Christensen
Nicholas J Fustino
Kenneth S Chen
Anthony J Hooten
Heather Nelson
Jacquelyn K Kuriger
Dinesh Rakheja
A Lindsay Frazier
Jenny N Poynter
机构
[1] University of Texas Southwestern Medical Center,Department of Pediatrics
[2] University of Texas Southwestern Medical Center,Department of Molecular Biology
[3] University of Texas Southwestern Medical Center,Department of Pathology
[4] Children’s Medical Center,Center for Cancer and Blood Disorders
[5] Division of Pediatric Epidemiology and Clinical Research,Department of Pediatrics
[6] University of Minnesota,Masonic Cancer Center
[7] University of Minnesota,Division of Epidemiology and Community Health
[8] Section of Biostatistics and Epidemiology,Department of Community and Family Medicine
[9] Dartmouth Medical School,undefined
[10] Dana Farber Cancer Institute,undefined
来源
BMC Cancer | / 13卷
关键词
Germ Cell Tumor; Teratoma; DNA Methylation; Imprinting;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 255 条
[1]  
Smiraglia DJ(2002)Distinct epigenetic phenotypes in seminomatous and nonseminomatous testicular germ cell tumors Oncogene 21 3909-3916
[2]  
Szymanska J(2008)Global DNA hypomethylation in intratubular germ cell neoplasia and seminoma, but not in nonseminomatous male germ cell tumors Mod Pathol 21 1337-1344
[3]  
Kraggerud SM(2001)SNRPN methylation patterns in germ cell tumors as a reflection of primordial germ cell development Genes Chromosomes Cancer 32 342-352
[4]  
Lothe RA(2010)Global DNA methylation in fetal human germ cells and germ cell tumours: association with differentiation and cisplatin resistance J Pathol 221 433-442
[5]  
Peltomaki P(2009)Yolk sac tumor but not seminoma or teratoma is associated with abnormal epigenetic reprogramming pathway and shows frequent hypermethylation of various tumor suppressor genes Cancer Sci 100 698-708
[6]  
Plass C(2006)Involvement of adenomatous polyposis coli (APC) gene in testicular yolk sac tumor of infants Hum Pathol 37 48-53
[7]  
Netto GJ(2003)Hypermethylation of the RUNX3 gene promoter in testicular yolk sac tumor of infants Am J Pathol 163 387-391
[8]  
Nakai Y(2003)Aberrant methylation of the HIC1 promoter is a frequent event in specific pediatric neoplasms Clin Cancer Res 9 3674-3678
[9]  
Nakayama M(2011)Methylator phenotype of malignant germ cell tumours in children identifies strong candidates for chemotherapy resistance Br J Cancer 105 575-585
[10]  
Jadallah S(2001)Multipoint imprinting analysis indicates a common precursor cell for gonadal and nongonadal pediatric germ cell tumors Cancer Res 61 7268-7276