Effect of Oxidative Stress on the Structure and Function of Human Serum Albumin

被引：0
作者：
Makoto Anraku
Keishi Yamasaki
Toru Maruyama
Ulrich Kragh-Hansen
Masaki Otagiri
机构：
[1] Kumamoto University,Faculty of Pharmaceutical Sciences
[2] University of Aarhus,Department of Medical Biochemistry
来源：
Pharmaceutical Research | 2001年 / 18卷
关键词：
human serum albumin; oxidative stress; structural changes; warfarin binding; ketoprofen binding; esterase–like activity;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Purpose. Human serum albumin (HSA) was mildly oxidized by a metal–catalyzed oxidation system (MCO–HSA), chloramine–T (CT–HSA) or H2O2 (H2O2–HSA), and the effects of these treatments on the structural, drug–binding and esterase–like properties were studied.
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页码：632 / 639
页数：7
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