Infective endocarditis is an infection of cardiovascular structures which is typically caused by bacteria. Despite recent medical advances mortality reaches up to 26% which is even higher with mortality rates of up to 84% in complex cases leading to admission to intensive care units. The diagnosis is based on positive blood culture results with identical microorganisms and the demonstration of endocardial involvement. A rapid initiation of an adequate therapeutic regimen is important to prevent the patients from severe complications such as heart failure, uncontrolled infection or septic embolism. An early and targeted initiation of an antibiotic therapy after microbiologic testing is crucial for therapeutic success. The immediate cooperation of Cardiologists, Microbiologists, Infectious Disease Specialists and Cardiac Surgeons is highly recommended to allow an adequate medical and surgical treatment without delay in complex cases. Antibiotic treatment has to be continued postoperatively.
机构:
Assoc Pour Etude & Prevent Endocardite Infectieus, Paris, France
INSERM, Ctr Invest Clin 007, AP HP, Hop Univ Bichat, Bichat, France
Univ Paris 07, Unite Format & Rech Med Bichat, INSERM, U738, Bichat, FranceUniv Franche Comte, Ctr Hosp Reg Univ, Serv Malad Infect & Trop, F-25030 Besancon, France
机构:
La Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Arregle, Florent
Iline, Nicolas
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La Timone Hosp, AP HM, BioSTIC, Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Iline, Nicolas
Giorgi, Roch
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Aix Marseille Univ, SESSTIM, AP HM, INSERM,IRD,BioSTIC, Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Giorgi, Roch
Philip, Mary
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La Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Philip, Mary
Hubert, Sandrine
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La Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Hubert, Sandrine
Gouriet, Frederique
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Aix Marseille Univ, IHU Mediterranee Infect, AP HM, IRD,MEPHI, Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Gouriet, Frederique
Casalta, Jean Paul
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Aix Marseille Univ, IHU Mediterranee Infect, AP HM, IRD,MEPHI, Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Casalta, Jean Paul
Collart, Frederic
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La Timone Hosp, Dept Cardiac Surg, Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Collart, Frederic
Riberi, Alberto
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La Timone Hosp, Dept Cardiac Surg, Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Riberi, Alberto
Martel, Helene
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La Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Martel, Helene
Renard, Sebastien
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La Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Renard, Sebastien
Camoin, Laurence
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Aix Marseille Univ, IHU Mediterranee Infect, AP HM, IRD,MEPHI, Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Camoin, Laurence
Casalta, Anne Claire
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La Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Casalta, Anne Claire
Lepidi, Hubert
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Aix Marseille Univ, IHU Mediterranee Infect, AP HM, IRD,MEPHI, Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Lepidi, Hubert
Raoult, Didier
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Aix Marseille Univ, IHU Mediterranee Infect, AP HM, IRD,MEPHI, Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Raoult, Didier
Drancourt, Michel
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Aix Marseille Univ, IHU Mediterranee Infect, AP HM, IRD,MEPHI, Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Drancourt, Michel
Habib, Gilbert
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La Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France
Aix Marseille Univ, IHU Mediterranee Infect, AP HM, IRD,MEPHI, Marseille, FranceLa Timone Hosp, AP HM, Serv Cardiol, Cardiol Dept, Blvd Jean Moulin, F-13005 Marseille, France