C-erbB-2 overexpression and survival in early onset breast cancer

被引：0
作者：
Måns Agrup
Olle Stäl
Karen Olsen
Sten Wingren
机构：
[1] Linköping University,Department of Biomedicine and Surgery, Division of Oncology, Faculty of Health Sciences
[2] Linköping University,Department of Health and Environment, Division of Pathology and Forensic Medicine, Faculty of Health Sciences
来源：
Breast Cancer Research and Treatment | 2000年 / 63卷
关键词：
breast cancer; early onset; immunohistochemistry; prognostic factors; young age;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Young breast cancer patients have a decreased survival rate and it has been demonstrated that young age is an independent predictor of adverse prognosis. Overexpression of c-erbB-2 protein (also known as HER-2/neu) has been shown to be a prognostic indicator in breast cancer in general and especially among patients with axillary nodal metastases. The present study was initiated to determine the prognostic significance of c-erbB-2 protein overexpression in early onset breast cancer.
引用
收藏
页码：23 / 29
页数：6
相关论文
共 224 条
[1]  
Walker RA(1996)Breast carcinomas in young women ( Br J Cancer 74 1796-1800
[2]  
Lees E(1993)35 years) are different Lancet 341 1039-1043
[3]  
Webb MB(1996)Age as a prognostic factor in premenopausal breast carcinoma Cancer 77 97-103
[4]  
Dearing SJ(1994)Younger women with breast carcinoma have a poorer prognosis than older women J Clin Oncol 12 888-89
[5]  
de la Rochefordière A(1986)Relationship of patient age to pathologic features of the tumor and prognosis for patients with stage I or II breast cancer Cancer 57 2217-2221
[6]  
Asselain B(1986)Age as a prognostic factor in breast cancer N Engl J Med 315 559-563
[7]  
Campana F(1995)The relationship between survival and age at diagnosis in breast cancer Int J Cancer 62 138-144
[8]  
Scholl S(1994)Age as a prognostic factor in breast cancer: Relationship to pathologic and biologic features Biochim Biophys Acta 1198 165-184
[9]  
Fenton J(1998)The biology of Eur J Cancer 34 791-808
[10]  
Vilcoq JR(1990) and its role in cancer Cancer Res 50 4332-4337
12345678910