Cholesterol biotransformation to androsta-1,4-diene-3,17-dione by growing cells of Chryseobacterium gleum

被引：0

作者：

Priti N. Chaudhari

Bhushan L. Chaudhari

Sudhir B. Chincholkar

机构：

[1] North Maharashtra University,School of Life Sciences

来源：

Biotechnology Letters | 2010年 / 32卷

关键词：

Androsta-1,4-diene-3,17-dione; Biotransformation; Cholesterol;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Cholesterol oxidase activity was studied during biotransformation of cholesterol to androsta-1,4-diene-3,17-dione (ADD) by Chryseobacterium gleum. Spent LB media, containing cholesterol (3 mM≈1 g l−1) where the bacterium was grown for 24 h, at 30°C with constant shaking at 120 rpm, had the highest enzyme activity (167 U mg−1). The growing cells produced 0.076 g ADD from 1 g cholesterol l−1.

引用

页码：695 / 699

页数：4

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