Brugada syndrome: Recent advances and controversies

被引:39
作者
Antzelevitch C. [1 ]
Nof E. [1 ]
机构
[1] Gordon K. Moe Scholar, Masonic Medical Research Laboratory, Utica, NY 13501
关键词
Sodium Channel; Cilostazol; Brugada Syndrome; Right Bundle Branch Block; Precordial Lead;
D O I
10.1007/s11886-008-0060-y
中图分类号
学科分类号
摘要
The Brugada syndrome, first described as a new clinical entity in 1992, is widely recognized today as a form of inherited sudden cardiac arrest. The past 16 years witnessed a progressive increase in the number of reported cases and a dramatic proliferation of articles serving to define the clinical, genetic, cellular, ionic, and molecular aspects of the disease. This article provides a brief overview of recent advances in our understanding of the clinical presentation and molecular and cellular mechanisms and an update of existing controversies. © Current Medicine Group LLC 2008.
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页码:376 / 383
页数:7
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