The atypical antipsychotic clozapine impairs insulin secretion by inhibiting glucose metabolism and distal steps in rat pancreatic islets

[1] Freedman R(2003)Schizophrenia N Engl J Med 349 1738-1749

[2] Kane J(1988)Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine Arch Gen Psychiatry 45 789-796

[3] Honigfeld G(1995)Reduction of suicidality during clozapine treatment of neuroleptic-resistant schizophrenia: impact on risk-benefit assessment Am J Psychiatry 152 183-190

[4] Singer J(1999)Smoking and therapeutic response to clozapine in patients with schizophrenia Biol Psychiatry 46 125-129

[5] Meltzer H(1975)Clozapine and agranulocytosis (letter) Lancet ii 611-523

[6] Meltzer HY(2004)Schizophrenia, the metabolic syndrome and diabetes Diabet Med 21 515-1521

[7] Okayli G(1994)Diabetic ketoacidosis associated with clozapine treatment Am J Psychiatry 151 1520-723

[8] McEvoy JP(2001)Clozapine-associated diabetes Am J Med 111 716-64

[9] Freudenreich O(2002)Phenomenology of and risk factors for new-onset diabetes mellitus and diabetic ketoacidosis associated with atypical antipsychotics: an analysis of 45 published cases Ann Clin Psychiatry 14 59-254

[10] Wilson WH(2002)Atypical antipsychotic drug use and diabetes Psychother Psychosom 71 244-11

[1] Freedman R(2003)Schizophrenia N Engl J Med 349 1738-1749

[2] Kane J(1988)Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazine Arch Gen Psychiatry 45 789-796

[3] Honigfeld G(1995)Reduction of suicidality during clozapine treatment of neuroleptic-resistant schizophrenia: impact on risk-benefit assessment Am J Psychiatry 152 183-190

[4] Singer J(1999)Smoking and therapeutic response to clozapine in patients with schizophrenia Biol Psychiatry 46 125-129

[5] Meltzer H(1975)Clozapine and agranulocytosis (letter) Lancet ii 611-523

[6] Meltzer HY(2004)Schizophrenia, the metabolic syndrome and diabetes Diabet Med 21 515-1521

[7] Okayli G(1994)Diabetic ketoacidosis associated with clozapine treatment Am J Psychiatry 151 1520-723

[8] McEvoy JP(2001)Clozapine-associated diabetes Am J Med 111 716-64

[9] Freudenreich O(2002)Phenomenology of and risk factors for new-onset diabetes mellitus and diabetic ketoacidosis associated with atypical antipsychotics: an analysis of 45 published cases Ann Clin Psychiatry 14 59-254

[10] Wilson WH(2002)Atypical antipsychotic drug use and diabetes Psychother Psychosom 71 244-11