Factors predicting disease progression in C9ORF72 ALS patients

[1] Trojsi F(2020)Genetics and sex in the pathogenesis of amyotrophic lateral sclerosis (ALS): is there a link? Int J Mol Sci 21 3647-1338

[2] D'Alvano G(2013)The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS Science 339 1335-558

[3] Bonavita S(2018)C9orf72-mediated ALS and FTD: multiple pathways to disease Nat Rev Neurol 14 544-1329

[4] Tedeschi G(2016)Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease Sci Transl Med 8 347ra93-1225

[5] Mori K(2016)C9orf72 is required for proper macrophage and microglial function in mice Science 351 1324-35

[6] Weng SM(2013)Autoimmune disease preceding amyotrophic lateral sclerosis: an epidemiologic study Neurology 81 1222-159

[7] Arzberger T(2016)Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: completing the picture Neurol Neuroimmunol Neuroinflamm 3 29-345

[8] May S(2018)Prevalence of immunological diseases in a Finnish frontotemporal lobar degeneration cohort with the C9orf72 repeat expansion carriers and non-carriers J Neuroimmunol 321 150-34

[9] Rentzsch K(2019)C9orf72 intermediate alleles in patients with amyotrophic lateral sclerosis, systemic lupus erythematosus, and rheumatoid arthritis Neuromolecular Med 21 333-94

[10] Kremmer E(2014)The widening spectrum of C9ORF72-related disease; genotype/phenotype correlations and potential modifiers of clinical phenotype Acta Neuropathol 127 229-8

[1] Trojsi F(2020)Genetics and sex in the pathogenesis of amyotrophic lateral sclerosis (ALS): is there a link? Int J Mol Sci 21 3647-1338

[2] D'Alvano G(2013)The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS Science 339 1335-558

[3] Bonavita S(2018)C9orf72-mediated ALS and FTD: multiple pathways to disease Nat Rev Neurol 14 544-1329

[4] Tedeschi G(2016)Loss-of-function mutations in the C9ORF72 mouse ortholog cause fatal autoimmune disease Sci Transl Med 8 347ra93-1225

[5] Mori K(2016)C9orf72 is required for proper macrophage and microglial function in mice Science 351 1324-35

[6] Weng SM(2013)Autoimmune disease preceding amyotrophic lateral sclerosis: an epidemiologic study Neurology 81 1222-159

[7] Arzberger T(2016)Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: completing the picture Neurol Neuroimmunol Neuroinflamm 3 29-345

[8] May S(2018)Prevalence of immunological diseases in a Finnish frontotemporal lobar degeneration cohort with the C9orf72 repeat expansion carriers and non-carriers J Neuroimmunol 321 150-34

[9] Rentzsch K(2019)C9orf72 intermediate alleles in patients with amyotrophic lateral sclerosis, systemic lupus erythematosus, and rheumatoid arthritis Neuromolecular Med 21 333-94

[10] Kremmer E(2014)The widening spectrum of C9ORF72-related disease; genotype/phenotype correlations and potential modifiers of clinical phenotype Acta Neuropathol 127 229-8