292 A Genome-Wide Association Study of Spontaneous Preterm Delivery

被引：0
|
作者：
H Boyd
B Feenstra
F Geller
E Feingold
K Ryckman
J Shaffer
C Laurie
Q Zhang
K Doheny
E Pugh
T Manolio
M Marazita
M Melbye
J Murray
Geneva Consortium
机构：
[1] Epidemiology Research,
[2] Statens Serum Institut,undefined
[3] Human Genetics,undefined
[4] University of Pittsburgh,undefined
[5] Pediatrics,undefined
[6] University of Iowa,undefined
[7] Biostatistics,undefined
[8] University of Washington,undefined
[9] Institute of Genetic Medicine,undefined
[10] Johns Hopkins University,undefined
[11] National Human Genome Research Institute,undefined
[12] NIH,undefined
来源：
Pediatric Research | 2010年 / 68卷
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摘要：
Background and aims: Up to 40% of preterm deliveries (PTDs) may have a genetic component. PTD inheritance patterns are consistent with maternal genotype effects, fetal genotype effects via maternally-derived alleles, or both. However, while many candidate genes have been proposed, no common genetic variant has yet been confirmed as contributing to PTD. A genome-wide association study (GWAS) of PTD has never before been undertaken. Consequently, our objective was to examine maternal and fetal genetic contributions to spontaneous PTD in a GWAS.
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页码：150 / 150
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