Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma

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作者：
Markus W. Löffler
Christopher Mohr
Leon Bichmann
Lena Katharina Freudenmann
Mathias Walzer
Christopher M. Schroeder
Nico Trautwein
Franz J. Hilke
Raphael S. Zinser
Lena Mühlenbruch
Daniel J. Kowalewski
Heiko Schuster
Marc Sturm
Jakob Matthes
Olaf Riess
Stefan Czemmel
Sven Nahnsen
Ingmar Königsrainer
Karolin Thiel
Silvio Nadalin
Stefan Beckert
Hans Bösmüller
Falko Fend
Ana Velic
Boris Maček
Sebastian P. Haen
Luigi Buonaguro
Oliver Kohlbacher
Stefan Stevanović
Alfred Königsrainer
Hans-Georg Rammensee
机构：
[1] University Hospital Tübingen,Department of General, Visceral and Transplant Surgery
[2] University of Tübingen,Interfaculty Institute for Cell Biology, Department of Immunology
[3] German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ) Partner Site Tübingen,Department of Clinical Pharmacology
[4] University Hospital Tübingen,Institute for Translational Bioinformatics
[5] University Hospital Tübingen,Quantitative Biology Center (QBiC)
[6] University of Tübingen,Center for Bioinformatics
[7] University of Tübingen,Department of Computer Science
[8] Applied Bioinformatics,Institute of Medical Genetics and Applied Genomics
[9] Present address: European Molecular Biology Laboratory,NGS Competence Center Tübingen (NCCT)
[10] European Bioinformatics Institute (EMBL-EBI),Present address: Department of General and Visceral Surgery
[11] University Hospital Tübingen,Institute of Pathology and Neuropathology
[12] Present address: Immatics Biotechnologies GmbH,Interfaculty Institute for Cell Biology, Proteome Center Tübingen (PCT)
[13] University of Tübingen,Internal Medicine, Department for Oncology, Hematology, Immunology, Rheumatology and Pulmonology
[14] Schwarzwald-Baar Hospital,Cancer Immunoregulation Unit
[15] University Hospital Tübingen,undefined
[16] University of Tübingen,undefined
[17] University of Tübingen,undefined
[18] Istituto Nazionale per lo Studio e la Cura dei Tumori,undefined
[19] “Fondazione Pascale” – IRCCS,undefined
[20] Max Planck Institute for Developmental Biology,undefined
[21] Biomolecular Interactions,undefined
来源：
Genome Medicine | / 11卷
关键词：
Hepatocellular carcinoma; HLA; HLA ligandomics; Immunoinformatics; Immunotherapy; Liver cancer; Mass spectrometry; Multi-omics; Neoantigen; Next-generation sequencing; Peptide prediction; Personalized medicine;
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