Primary diffuse large B-cell lymphoma of ampulla of Vater: A rare case report

被引：3

作者：

Trivedi P. ^{[1
]}

Gupta A. ^{[1
]}

Pasricha S. ^{[1
]}

机构：

[1] Department of Pathology, Gujarat Cancer and Research Institute, M.P. Shah Cancer Hospital, Asarwa, Ahmedabad

来源：

Journal of Gastrointestinal Cancer | 2012年 / 43卷 / 2期

关键词：

Ampulla of Vater; Diffuse large B-cell lymphoma; Lymphoma; Periampullary region;

D O I：

10.1007/s12029-010-9202-8

中图分类号：

学科分类号：

摘要：

Introduction: Primary lymphomas of the ampulla of Vater are extremely rare. Among these most frequent are follicular lymphomas followed by mucosa-associated lymphoid tissue-type lymphoma. Case Report: We report a case of a 36-year-old female diagnosed with diffuse large B-cell lymphoma (DLBCL) of the ampulla of Vater. Endoscopic biopsy was non-diagnostic. Whipple's resection was performed. The patient was given six cycles of chemotherapy. One year later, the patient developed recurrence at the anastomotic site and again treated with combination chemotherapy. Patient is doing well after 2 years of initial surgery. Discussion: Tumors of the ampulla of Vater are included in the pancreaticobiliary group of neoplasms; in some instances, it is almost impossible to ascertain the exact origin of the tumor anatomically. The patients of primary lymphoma of the ampulla of Vater may have a varied clinical presentation or may be completely asymptomatic and detected during routine medical check-ups for gastric cancer screening. Conclusion: We present a rare case of primary DLBCL of the periampullary region. Due to the rarity of these lesions, their ability to masquerade as periampullary carcinomas, and the fact that these tumors show a good response to chemotherapy, an early diagnosis is desirable. © Springer Science+Business Media, LLC 2010.

引用

页码：340 / 343

页数：3

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