Simulation of daily soft multifocal contact lenses using SimVis Gekko: from in-vitro and computational characterization to clinical validation

被引:2
作者
Esteban-Ibanez, Eduardo [1 ,2 ]
Montagud-Martinez, Diego [3 ,4 ]
Sawides, Lucie [1 ,2 ]
Zaytouny, Amal [2 ]
de Castro, Alberto [2 ]
Siso-Fuertes, Irene [1 ]
Barcala, Xoana [1 ]
Pinero, David P. [5 ]
Furlan, Walter D. [4 ]
Dorronsoro, Carlos [1 ,2 ]
Gambra, Enrique [1 ]
机构
[1] 2EyesVision SL, Plaza Encina 10,Nucleo 3,Planta 4a, Madrid 28760, Spain
[2] Spanish Natl Res Council, Inst Opt Daza de Valdes, IO CSIC, Madrid, Spain
[3] Univ Politecn Valencia, Ctr Tecnol Fis, Valencia, Spain
[4] Univ Valencia, Dept Opt & Optometria & Ciencias Vis, Valencia, Spain
[5] Univ Alicante, Dept Opt Farmacol & Anat, Alicante, Spain
关键词
POWER PROFILES; VISUAL-ACUITY; VISION; FOCUS;
D O I
10.1038/s41598-024-59178-1
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Multifocal contact lenses (MCLs) are one of the solutions to correct presbyopia, but their adoption is not widespread. To address this situation, visual simulators can be used to refine the adaptation process. This study aims to obtain accurate simulations for a visual simulator (SimVis Gekko; 2EyesVision) of daily soft MCL designs from four manufacturers. In-vitro characterization of these MCLs-several powers and additions- was obtained using NIMO TR-1504. From the averaged relative power profiles across powers, phase maps were reconstructed and the Through-Focus Visual Strehl metric was calculated for each MCL design. The SimVis Gekko simulation corresponding to each MCL design was obtained computationally and bench-validated. Finally, the MCL simulations were clinically validated involving presbyopic patients. The clinical validation results show a good agreement between the SimVis Gekko simulations and the real MCLs for through-focus visual acuity (TF-VA) curves and VA at three real distances. All MCL designs showed a partial correlation higher than 0.90 and a Root Mean Square Error below 0.07 logMAR between the TF-VA of simulations and Real MCLs across subjects. The validity of the simulation approach using SimVis Gekko and in-vitro measurements was confirmed in this study, opening the possibility to accelerate the adaptation of MCLs.
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页数:11
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