4-Hydroxy-2-quinolones 138. Synthesis and study of structure-biological activity relationships in a series of 1-hydroxy-3-oxo-5,6-dihydro-3H-pyrrolo[3, 2,1-ij]quinoline-2-carboxylic acid anilides

被引：0
作者：
Ukrainets I.V. [1 ]
Mospanova E.V. [1 ]
Bereznyakova N.L. [1 ]
Naboka O.I. [1 ]
机构：
[1] National University of Pharmacy
来源：
Chemistry of Heterocyclic Compounds | 2007年 / 43卷 / 12期
关键词：
4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carboxylic acids; Amidation; Anilides; Antitubercular activity; Diuretics;
D O I：
10.1007/s10593-007-0237-0
中图分类号：
学科分类号：
摘要：
Two methods are discussed and the synthesis of a series of 1-hydroxy-3-oxo-5,6-dihydro-3H-pyrrolo[3,2,1-ij]quinoline-2-carboxylic acid anilides has been carried out. The antitubercular activity and the effect on the urinary function of the kidney have been studied for the compounds prepared. A structure-biological activity relationship is discussed. © 2007 Springer Science+Business Media, Inc.
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页码：1532 / 1539
页数：7
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