Influences of CYP2D6*10 polymorphisms on the pharmacokinetics of iloperidone and its metabolites in Chinese patients with schizophrenia: a population pharmacokinetic analysis

被引：0
作者：
Qi Pei
Lu Huang
Jie Huang
Jing-kai Gu
Yun Kuang
Xiao-cong Zuo
Jun-jie Ding
Hong-yi Tan
Cheng-xian Guo
Shi-kun Liu
Guo-ping Yang
机构：
[1] Third Xiangya Hospital,Center of Clinical Pharmacology and Pharmacy Department
[2] Central South University,undefined
[3] Drug Metabolism Research Center of Jilin University,undefined
[4] Children's Hospital of Fudan University,undefined
来源：
Acta Pharmacologica Sinica | 2016年 / 37卷
关键词：
schizophrenia; iloperidone; gene polymorphisms; 10; population pharmacokinetics;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：1499 / 1508
页数：9
相关论文
共 50 条
  • [1] Influences of CYP2D6*10 polymorphisms on the pharmacokinetics of iloperidone and its metabolites in Chinese patients with schizophrenia: a population pharmacokinetic analysis
    Pei, Qi
    Huang, Lu
    Huang, Jie
    Gu, Jing-kai
    Kuang, Yun
    Zuo, Xiao-cong
    Ding, Jun-jie
    Tan, Hong-yi
    Guo, Cheng-xian
    Liu, Shi-kun
    Yang, Guo-ping
    [J]. ACTA PHARMACOLOGICA SINICA, 2016, 37 (11) : 1499 - 1508
  • [2] The association between CYP2D6 genetic polymorphism and schizophrenia in a Chinese population
    Zhou, Jian
    Wang Yajie
    Wang, Gang
    Chen Xueyan
    Lv, Hong
    Kang Xixiong
    [J]. PROGRESS ON POST-GENOME TECHNOLOGIES, 2007, : 453 - 455
  • [3] Influence of CYP2D6 polymorphisms on symptomatology and sideeffects of patients with schizophrenia in Malaysia
    Zahari, Zalina
    Salleh, Mohd Razali
    Teh, Lay Kek
    Ismail, Rusli
    [J]. MALAYSIAN JOURNAL OF MEDICAL SCIENCES, 2009, 16 (03): : 13 - 21
  • [4] A population pharmacokinetic evaluation of the influence of CYP2D6 genotype on risperidone metabolism in patients with acute episode of schizophrenia
    Locatelli, Igor
    Kastelic, Matej
    Koprivsek, Jure
    Kores-Plesnicar, Blanka
    Mrhar, Ales
    Dolzan, Vita
    Grabnar, Iztok
    [J]. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2010, 41 (02) : 289 - 298
  • [5] CYP2D6 polymorphisms and the risk of tardive dyskinesia in schizophrenia:: a meta-analysis
    Patsopoulos, NA
    Ntzani, EE
    Zintzaras, E
    Ioannidis, JPA
    [J]. PHARMACOGENETICS AND GENOMICS, 2005, 15 (03) : 151 - 158
  • [6] Debrisoquine 4-hydroxylase (CYP2D6) genetic polymorphisms and susceptibility to schizophrenia in Chinese patients from Taiwan
    Chen, CH
    Hung, CC
    Wei, FC
    Koong, FJ
    [J]. PSYCHIATRIC GENETICS, 2001, 11 (03) : 153 - 155
  • [7] Genetic polymorphisms for drug metabolism (CYP2D6) and tardive dyskinesia in schizophrenia
    Kapitany, T
    Meszaros, K
    Lenzinger, E
    Schindler, SD
    Barnas, C
    Fuchs, K
    Sieghart, W
    Aschauer, HN
    Kasper, S
    [J]. SCHIZOPHRENIA RESEARCH, 1998, 32 (02) : 101 - 106
  • [8] CYP2D6 polymorphisms are associated with effects of risperidone on neurocognitive performance in schizophrenia
    Zeng, Lei
    Kang, ChuanYuan
    Yuan, Jing
    Zhang, Yan
    Wei, Yujun
    Xu, Li
    Zhou, Fang
    Yang, JianZhong
    [J]. SCHIZOPHRENIA RESEARCH, 2017, 188 : 50 - 51
  • [9] Association of CYP2D6 polymorphisms and extrapyramidal symptoms in schizophrenia patients receiving risperidone: a retrospective study
    Ito, Takahiro
    Yamamoto, Kazuhiro
    Ohsawa, Fuminori
    Otsuka, Ikuo
    Hishimoto, Akitoyo
    Sora, Ichiro
    Hirai, Midori
    Yano, Ikuko
    [J]. JOURNAL OF PHARMACEUTICAL HEALTH CARE AND SCIENCES, 2018, 4
  • [10] Association of CYP2D6 polymorphisms and extrapyramidal symptoms in schizophrenia patients receiving risperidone: a retrospective study
    Takahiro Ito
    Kazuhiro Yamamoto
    Fuminori Ohsawa
    Ikuo Otsuka
    Akitoyo Hishimoto
    Ichiro Sora
    Midori Hirai
    Ikuko Yano
    [J]. Journal of Pharmaceutical Health Care and Sciences, 4 (1)
12345