Mass spectrometry-based proteomics as an emerging tool in clinical laboratories

被引：0
作者：
Alemayehu Godana Birhanu
机构：
[1] Addis Ababa University,Institute of Biotechnology
来源：
Clinical Proteomics | 2023年 / 20卷
关键词：
Mass spectrometry; Clinical proteomics; Diagnosis; Biomarker; Prognosis; Microbiology; Cancer; Metabolic Disorders;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Mass spectrometry (MS)-based proteomics have been increasingly implemented in various disciplines of laboratory medicine to identify and quantify biomolecules in a variety of biological specimens. MS-based proteomics is continuously expanding and widely applied in biomarker discovery for early detection, prognosis and markers for treatment response prediction and monitoring. Furthermore, making these advanced tests more accessible and affordable will have the greatest healthcare benefit.
引用
收藏
相关论文
共 385 条
  • [61] Nomura F(2018)Comprehensive single-shot proteomics with FAIMS on a hybrid orbitrap mass spectrometer Anal Chem 90 9529-85
  • [62] Principe S(2005)Sample preparation and digestion for proteomic analyses using spin filters Proteomics 5 1742-3
  • [63] Drake RR(2009)Universal sample preparation method for proteome analysis Nat Methods 6 359-6
  • [64] Wu CC(2014)Suspension trapping (STrap) sample preparation method for bottom-up proteomics analysis Proteomics 14 1006-9
  • [65] de Souza GA(2018)S-Trap, an ultrafast sample-preparation approach for shotgun proteomics J Proteome Res 17 2917-8
  • [66] de Godoy LM(2014)Ultrasensitive proteome analysis using paramagnetic bead technology Mol Syst Biol 10 757-32
  • [67] Mann M(2019)R2-P2 rapid‐robotic phosphoproteomics enables multidimensional cell signaling studies Mol Syst Biol 15 e9021-91
  • [68] Spreafico F(2016)Quantitative profiling of single formalin fixed tumour sections: proteomics for translational research Sci Rep 6 1-8
  • [69] Elschenbroich S(2018)Molecular characterization of ERBB2-amplified colorectal cancer identifies potential mechanisms of resistance to targeted therapies: a report of two instructive cases Mol Case Stud 4 a002535-14
  • [70] Gortzak-Uzan L(2014)Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells Nat Methods 11 319-73
234567891011