Mass spectrometry-based proteomics as an emerging tool in clinical laboratories

被引：0
作者：
Alemayehu Godana Birhanu
机构：
[1] Addis Ababa University,Institute of Biotechnology
来源：
Clinical Proteomics | 2023年 / 20卷
关键词：
Mass spectrometry; Clinical proteomics; Diagnosis; Biomarker; Prognosis; Microbiology; Cancer; Metabolic Disorders;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Mass spectrometry (MS)-based proteomics have been increasingly implemented in various disciplines of laboratory medicine to identify and quantify biomolecules in a variety of biological specimens. MS-based proteomics is continuously expanding and widely applied in biomarker discovery for early detection, prognosis and markers for treatment response prediction and monitoring. Furthermore, making these advanced tests more accessible and affordable will have the greatest healthcare benefit.
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  • [1] Jimenez CR(2014)Mass spectrometry-based proteomics: from cancer biology to protein biomarkers, drug targets, and clinical applications Am Soc Clin Oncol Educational Book 34 e504-10
  • [2] Verheul HM(2014)The role of protein interaction networks in systems biomedicine Comput Struct Biotechnol J 11 22-7
  • [3] Sevimoglu T(2020)Proteomic applications in antimicrobial resistance and clinical microbiology studies Infect Drug Resist 13 1785-63
  • [4] Arga KY(2012)A novel mass spectrometry–based assay for the accurate measurement of thyroglobulin from patient samples containing antithyroglobulin autoantibodies J Investig Med 60 1157-30
  • [5] Khodadadi E(2010)Falsely elevated whole-blood tacrolimus concentrations in a kidney‐transplant patient: potential hazards Transpl Int 23 227-32
  • [6] Clarke NJ(2003)Disease proteomics Nature 422 226-6
  • [7] Zhang Y(2013)Is clinical proteomics heading towards to “bench to bedside Transl Proteom 1 53-42
  • [8] Reitz RE(2012)How to get proteomics to the clinic? Issues in clinical proteomics, exemplified by CE-MS PROTEOMICS–Clinical Appl 6 437-36
  • [9] Rostaing L(2012)Implementation of proteomic biomarkers: making it work Eur J Clin Invest 42 1027-11
  • [10] Hanash S(2012)Mass spectrometry for translational proteomics: progress and clinical implications Genome Med 4 1-71
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