Transabdominal electrical stimulation (TES) for the treatment of slow-transit constipation (STC)

被引：0
作者：
John M. Hutson
Lauren Dughetti
Lefteris Stathopoulos
Bridget R. Southwell
机构：
[1] F Douglas Stephens Surgical Research Group,Murdoch Childrens Research Laboratory
[2] The Royal Children’s Hospital,Urology Department
[3] University of Melbourne,Department of Paediatrics
来源：
Pediatric Surgery International | 2015年 / 31卷
关键词：
Slow-transit constipation; Colonic dysmotility; Transcutaneous electrical stimulation;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Slow-transit constipation (STC) is a newly described subtype of intractable constipation in children which we originally identified with deficiency of substance P in axons supplying the proximal colonic muscle. When nuclear transit studies became available, the patients were found to have slow proximal colonic transit, and responded to antegrade enemas. Using the appendicostomy, we found that there was reduced frequency in propagating sequences throughout the colon. We began testing whether transcutaneous electrical stimulation (TES) could improve motility and symptoms, and over several trials have now shown that TES is remarkably effective in treating children with STC, with long-lasting effects. TES holds promise for treating STC, as well as a range of gastrointestinal motility disorders.
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页码：445 / 451
页数：6
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