Development of a construct-based risk assessment framework for genetic engineered crops

被引：0

作者：

M. P. Beker

P. Boari

M. Burachik

V. Cuadrado

M. Junco

S. Lede

M. A. Lema

D. Lewi

A. Maggi

I. Meoniz

G. Noé

C. Roca

C. Robredo

C. Rubinstein

C. Vicien

A. Whelan

机构：

[1] Bayer SA,

[2] Biotechnology Directorate,undefined

[3] Secretariat of Value Adding,undefined

[4] Indear,undefined

[5] Monsanto Argentina,undefined

[6] National Agri Food Health and Quality Service,undefined

[7] SENASA,undefined

[8] BASF Argentina,undefined

[9] National Scientific and Technical Research Council,undefined

[10] CONICET,undefined

[11] National University of Quilmes,undefined

[12] National Agricultural Research Institute,undefined

[13] INTA,undefined

[14] Syngenta Agro,undefined

[15] Dow Agroscience SA,undefined

[16] Chacra Experimental Agricola Santa Rosa,undefined

[17] ILSI Argentina,undefined

[18] University of Buenos Aires and CERA,undefined

[19] Sr Consultant,undefined

来源：

Transgenic Research | 2016年 / 25卷

关键词：

Genetic engineering; Risk assessment; Construct similarity; Familiarity; Problem Formulation;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Experience gained in the risk assessment (RA) of genetically engineered (GE) crops since their first experimental introductions in the early nineties, has increased the level of familiarity with these breeding methodologies and has motivated several agencies and expert groups worldwide to revisit the scientific criteria underlying the RA process. Along these lines, the need to engage in a scientific discussion for the case of GE crops transformed with similar constructs was recently identified in Argentina. In response to this need, the Argentine branch of the International Life Sciences Institute (ILSI Argentina) convened a tripartite working group to discuss a science-based evaluation approach for transformation events developed with genetic constructs which are identical or similar to those used in previously evaluated or approved GE crops. This discussion considered new transformation events within the same or different species and covered both environmental and food safety aspects. A construct similarity concept was defined, considering the biological function of the introduced genes. Factors like environmental and dietary exposure, familiarity with both the crop and the trait as well as the crop biology, were identified as key to inform a construct-based RA process.

引用

页码：597 / 607

页数：10

共 114 条

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