Ten years of anti-vascular endothelial growth factor therapy

被引:0
作者
Napoleone Ferrara
Anthony P. Adamis
机构
[1] University of California,
[2] San Diego,undefined
[3] Genentech,undefined
[4] Inc.,undefined
来源
Nature Reviews Drug Discovery | 2016年 / 15卷
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摘要
Over the past 10 years, targeting vascular endothelial growth factor A (VEGFA) has been widely pursued in the treatment of various cancers and ophthalmic diseases. Here, Ferrara and Adamis provide an overview of the discovery of VEGFA and the development of anti-VEGFA therapies, addressing key challenges and issues that remain in the application of these agents.
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页码:385 / 403
页数:18
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