Activation of liver X receptors inhibits pancreatic islet beta cell proliferation through cell cycle arrest

Saltiel AR(2001)New perspectives into the molecular pathogenesis and treatment of type 2 diabetes Cell 104 517-529

Del Guerra S(2005)Functional and molecular defects of pancreatic islets in human type 2 diabetes Diabetes 54 727-735

Lupi R(2006)Islet beta cell failure in type 2 diabetes J Clin Invest 116 1802-1812

Marselli L(2006)Molecular control of cell cycle progression in the pancreatic beta-cell Endocr Rev 27 356-370

Prentki M(2007)Molecular regulation of pancreatic beta-cell mass development, maintenance, and expansion J Mol Endocrinol 38 193-206

Nolan CJ(2007)All beta cells contribute equally to islet growth and maintenance PLoS Biol 5 e163-D19

Cozar-Castellano I(2000)Cell cycle control of pancreatic beta cell proliferation Front Biosci 5 D1-2876

Fiaschi-Taesch N(2007)Essential role of Skp2-mediated p27 degradation in growth and adaptive expansion of pancreatic beta cells J Clin Invest 117 2869-182

Bigatel TA(2005)Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice Nat Med 11 175-338

Ackermann AM(2006)Intrinsic regulators of pancreatic beta-cell proliferation Annu Rev Cell Dev Biol 22 311-2956

Saltiel AR(2001)New perspectives into the molecular pathogenesis and treatment of type 2 diabetes Cell 104 517-529

Del Guerra S(2005)Functional and molecular defects of pancreatic islets in human type 2 diabetes Diabetes 54 727-735

Lupi R(2006)Islet beta cell failure in type 2 diabetes J Clin Invest 116 1802-1812

Marselli L(2006)Molecular control of cell cycle progression in the pancreatic beta-cell Endocr Rev 27 356-370

Prentki M(2007)Molecular regulation of pancreatic beta-cell mass development, maintenance, and expansion J Mol Endocrinol 38 193-206

Nolan CJ(2007)All beta cells contribute equally to islet growth and maintenance PLoS Biol 5 e163-D19

Cozar-Castellano I(2000)Cell cycle control of pancreatic beta cell proliferation Front Biosci 5 D1-2876

Fiaschi-Taesch N(2007)Essential role of Skp2-mediated p27 degradation in growth and adaptive expansion of pancreatic beta cells J Clin Invest 117 2869-182

Bigatel TA(2005)Deletion of Cdkn1b ameliorates hyperglycemia by maintaining compensatory hyperinsulinemia in diabetic mice Nat Med 11 175-338

Ackermann AM(2006)Intrinsic regulators of pancreatic beta-cell proliferation Annu Rev Cell Dev Biol 22 311-2956