共 144 条
[1]
Shih C(1997)LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes Cancer Res 57 1116-1123
[2]
Chen VJ(2004)Randomized phase III trial of pemetrexed versus docetaxel in patients with non-small-cell lung cancer previously treated with chemotherapy J Clin Oncol 22 1589-1597
[3]
Gossett LS(2012)Association between expression of thymidylate synthase, dihydrofolate reductase, and glycinamide ribonucleotide formyltransferase and efficacy of pemetrexed in advanced non-small cell lung cancer Anticancer Res 32 4589-4596
[4]
Gates SB(2013)Thymidylate synthase expression determines pemetrexed targets and resistance development in tumour cells PLoS ONE 8 e63338-166
[5]
MacKellar WC(2010)Significance of thymidylate synthase for resistance to pemetrexed in lung cancer Cancer Sci 101 161-838
[6]
Habeck LL(2006)A phase II trial of pemetrexed in advanced breast cancer: clinical response and association with molecular target expression Clin Cancer Res 12 832-229
[7]
Shackelford KA(2002)Thymidylate synthase: a critical target for cancer chemotherapy Clin Colorectal Cancer 1 220-313
[8]
Mendelsohn LG(1997)Thymidylate synthase expression and response to neoadjuvant chemotherapy in patients with advanced head and neck cancer J Natl Cancer Inst 89 308-1539
[9]
Soose DJ(2010)Thymidylate synthase but not excision repair cross-complementation group 1 tumor expression predicts outcome in patients with malignant pleural mesothelioma treated with pemetrexed-based chemotherapy J Clin Oncol 28 1534-3551
[10]
Patel VF(2008)Phase III study comparing cisplatin plus gemcitabine with cisplatin plus pemetrexed in chemotherapy-naive patients with advanced-stage non-small-cell lung cancer J Clin Oncol 26 3543-1596