Interaction of 1-(β-oxyethyl)-2-methyl-5-nitroimidazole with the surface of highly dispersed silica

被引：1

作者：

Gabchak A.L. ^{[1
]}

Nosach L.V. ^{[1
]}

Voronin E.F. ^{[1
]}

Gerashchenko I.I. ^{[1
]}

Chuiko A.A. ^{[1
]}

机构：

[1] Institute of Surface Chemistry, National Academy of Sciences of Ukraine, Kiev, 03164

来源：

Journal of Applied Spectroscopy | 2005年 / 72卷 / 6期

关键词：

1-(β-oxyethyl)-2-methyl-5-nitroimidazole; Adsorption; Highly dispersed silica; IR spectroscopy; Metronidazole;

D O I：

10.1007/s10812-006-0003-6

中图分类号：

学科分类号：

摘要：

Using the IR spectroscopy method, it has been established that formation of a monolayer 1-(β-oxyethyl)-3-methyl-5-nitroimidazole (metronidazole) on the surface of nonporous amorphous highly dispersed silica (Ssp = 230 m2/g) occurs during its absorption in an amount of 0.6 mmole/g. Such a content of adsorbate corresponds to the concentration of free silanol groups that are main active centers of the surface. Based on the analysis of the IR spectra of the specimens obtained and the dependence of the degree of perturbation of silanol groups on the content of adsorbed metronidazole, the structure of the surface adsorption complexes is suggested. ©2005 Springer Science+Business Media, Inc.

引用

页码：786 / 790

页数：4

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