Vascular Erectile Dysfunction and Subclinical Cardiovascular Disease

被引：16

作者：

Gowani Z. ^{[1
]}

Uddin S.M.I. ^{[2
]}

Mirbolouk M. ^{[2
]}

Ayyaz D. ^{[2
]}

Billups K.L. ^{[3
]}

Miner M. ^{[4
]}

Feldman D.I. ^{[2
,5
]}

Blaha M.J. ^{[2
]}

机构：

[1] Johns Hopkins Bayview Medical Center, Baltimore, MD

[2] Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins University School of Medicine, Baltimore, MD

[3] Department of Surgery, Meharry Medical College, Nashville, TN

[4] Department of Family Medicine, Alpert Medical School of Brown University, Providence, RI

[5] The University of Miami Miller School of Medicine, Miami, FL

来源：

Current Sexual Health Reports | 2017年 / 9卷 / 4期

基金：

美国国家卫生研究院;

关键词：

Cardiovascular disease; Coronary calcium score; Erectile dysfunction; Princeton III Consensus; Risk assessment; Subclinical disease;

D O I：

10.1007/s11930-017-0137-y

中图分类号：

学科分类号：

摘要：

Purpose of Review: We review the recent literature on the hypothesized temporal relationship between subclinical cardiovascular disease (CVD), vascular erectile dysfunction (ED), and clinical CVD. In addition, we combine emerging research with expert consensus guidelines such as The Princeton Consensus III to provide a preventive cardiologist’s perspective toward an ideal approach to evaluating and managing CVD and ED risk in patients. Recent Findings: Development of ED was found to occur during the progression from subclinical CVD to clinical CVD. A strong association was observed between subclinical CVD as assessed by coronary artery calcium (CAC) and carotid plaque and subsequent ED, providing evidence for the role of subclinical CVD in predicting ED. ED is also identified as a substantial independent risk factor for overt clinical CVD, and ED symptoms may precede CVD symptoms by 2–3 years. Summary: Given the body of evidence on the relationship between subclinical CVD, ED, and clinical CVD, we recommend that all men with vascular ED should undergo cardiovascular risk assessment. We further recommend using CAC scores for advanced risk assessment in patients at low–intermediate to intermediate risk (5–20% CVD risk), with risk driving subsequent lifestyle and pharmacologic treatment decisions. © 2017, Springer Science+Business Media, LLC.

引用

页码：305 / 312

页数：7

共 39 条

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