Use of Cannabinoids for Spasticity and Pain Management in MS

被引:0
作者
Hardeep Chohan
Ariele L. Greenfield
Vijayshree Yadav
Jennifer Graves
机构
[1] University of California,Department of Neurology
[2] San Francisco,Department of Neurology
[3] Oregon Health and Science University,undefined
来源
Current Treatment Options in Neurology | 2016年 / 18卷
关键词
Multiple sclerosis; Cannabinoids; Spasticity; Pain; Tetrahydrocannabinol; Cannabidiol;
D O I
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学科分类号
摘要
Several randomized trials have demonstrated potential benefit of cannabis derivatives in the symptomatic treatment of multiple sclerosis (MS) patients. These provide class 1 and 2 evidence for cannabinoid product use for spasticity and pain in these patients. The precise best ratio or doses are not yet clear. The safety and potential long-term effects of these products on cognitive function in people with MS have not been evaluated. Since short-term memory and processing speed can be significantly impaired in many people with MS, the concern of potential cognitive impairment related to cannabis products needs consideration in clinical care and should be addressed in longer, prospective studies.
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