Twists and turns of invasion

被引：0
作者：
Geoffrey Childs
Jeffrey E. Segall
机构：
[1] Albert Einstein College of Medicine,Geoffrey Childs and Jeffrey E. Segall are at the Department of Pathology
[2] Bronx,Jeffrey E. Segall is also at the Department of Anatomy and Structural Biology
[3] New York 10461,undefined
[4] USA,undefined
[5] Albert Einstein College of Medicine,undefined
[6] Bronx,undefined
[7] New York 10461,undefined
[8] USA,undefined
来源：
Nature Cell Biology | 2012年 / 14卷
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摘要：
The transcription factor Twist1 is overexpressed in tumours and can induce the epithelial–mesenchymal transition, resulting in increased invasiveness. Twist1 is now shown to regulate cancer cell migration and invasion in three-dimensional environments by activating the RAC1 GTPase through suppression of a let-7 microRNA family member.
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页码：337 / 339
页数：2
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