Blood Vessel Segmentation via Neural Network in Histological Images

被引:0
作者
Roberto Rodríguez
Teresa E. Alarcón
Juan J. Abad
机构
[1] Institute of Cybernetics,
[2] Mathematics and Physics (ICIMAF),undefined
[3] Group of Digital Signal Processing,undefined
来源
Journal of Intelligent and Robotic Systems | 2003年 / 36卷
关键词
angiogenesis process; Gauss filter; image segmentation; neural network;
D O I
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中图分类号
学科分类号
摘要
In this paper we utilize the Kohonen's self-organizing feature map to segment blood vessels from biopsies in tumor tissue. The ability of this kind of neural network to recognize very complex patterns makes it an effective computational tool for the segmentation. We propose a strategy of blood vessels segmentation using a neural network, taking into account the quality of our images and its features: complexity in shape and variability in size. Segmentation results are contingently manually corrected. The proposed segmentation strategy is tested on manual segmentation, where segmentation errors of less than 3.5% are observed. This work is a part of a global image analysis process and these images will be subject to a further morphometrical analysis in order to diagnose and prognosticate automatically malignant tumours.
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页码:451 / 465
页数:14
相关论文
共 33 条
[1]  
Boschner B. H.(1995)Angiogenesis in bladder cancer: Relationship between microvessel density and tumor prognosis J. National. Cancer Inst. 87 21 1603-1612
[2]  
Cote R. J.(1998)Color image segmentation for bladder cancer diagnosis Math. Comput. Modeling 27 103-120
[3]  
Weidner N.(1992)Angiogenesis: an update Histol. Histopath. 9 807-843
[4]  
Groshen S.(1984)The structure of images Biological Cybernetics 50 363-370
[5]  
Chen S. C.(1990)The self-organizing map Proc. IEEE 78 1464-1480
[6]  
Skinner D. G.(1996)Microvessel density is a prognostic indicator for patients with astroglial brain tumors Cancer 77 2 362-372
[7]  
Nichols P. W.(1990)A multiresolution hierarchical approach to image segmentation based on intensity extreme IEEE Trans. Pattern Anal. Mach. Intelligence 12 529-541
[8]  
Chin-Hsing C.(2001)MADIP: Morphometrical analysis by digital image processing Proc. of the IX Spanish Symposium on Pattern Recognition and Image Analysis I 291-298
[9]  
Lee J.(1991)Tumor angiogenesis and metastasis – correlation in invasive breast carcinoma N. Engl. J. Med. 324 1-8
[10]  
Wang J.(1997)Watershed-based segmentation of 3D MR data for volumen quatization Magnetic Resonance Imaging 15 679-688