RNA sensor MDA5 suppresses LINE-1 retrotransposition by regulating the promoter activity of LINE-1 5′-UTR

[1] Ablasser A(2014)TREX1 deficiency triggers cell-autonomous immunity in a cGAS-dependent manner J Immunol 192 5993-5997

[2] Hemmerling I(2004)The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter Proc Natl Acad Sci U S A 101 17264-17269

[3] Schmid-Burgk JL(2016)Interferon but not MxB inhibits foamy retroviruses Virology 488 51-60

[4] Behrendt R(2018)RNase H2, mutated in Aicardi-Goutieres syndrome, promotes LINE-1 retrotransposition EMBO J 37 e98506-752

[5] Roers A(2012)Human transposon tectonics Cell 149 740-1926

[6] Hornung V(2018)Interplay between RNASEH2 and MOV10 controls LINE-1 retrotransposition Nucleic Acids Res 46 1912-440

[7] Andrejeva J(2015)Aicardi-Goutieres syndrome and the type I interferonopathies Nat Rev Immunol 15 429-85

[8] Childs KS(2019)A balancing act: MDA5 in antiviral immunity and autoinflammation Trends Microbiol 27 75-1911

[9] Young DF(2013)Differential requirements for HIV-1 Vif-mediated APOBEC3G degradation and RUNX1-mediated transcription by core binding factor beta J Virol 87 1906-1870

[10] Carlos TS(2006)mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s Curr Biol 16 1865-1943

[1] Ablasser A(2014)TREX1 deficiency triggers cell-autonomous immunity in a cGAS-dependent manner J Immunol 192 5993-5997

[2] Hemmerling I(2004)The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN-beta promoter Proc Natl Acad Sci U S A 101 17264-17269

[3] Schmid-Burgk JL(2016)Interferon but not MxB inhibits foamy retroviruses Virology 488 51-60

[4] Behrendt R(2018)RNase H2, mutated in Aicardi-Goutieres syndrome, promotes LINE-1 retrotransposition EMBO J 37 e98506-752

[5] Roers A(2012)Human transposon tectonics Cell 149 740-1926

[6] Hornung V(2018)Interplay between RNASEH2 and MOV10 controls LINE-1 retrotransposition Nucleic Acids Res 46 1912-440

[7] Andrejeva J(2015)Aicardi-Goutieres syndrome and the type I interferonopathies Nat Rev Immunol 15 429-85

[8] Childs KS(2019)A balancing act: MDA5 in antiviral immunity and autoinflammation Trends Microbiol 27 75-1911

[9] Young DF(2013)Differential requirements for HIV-1 Vif-mediated APOBEC3G degradation and RUNX1-mediated transcription by core binding factor beta J Virol 87 1906-1870

[10] Carlos TS(2006)mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2s Curr Biol 16 1865-1943