Effect of iron limitation on slime production by Staphylococcus aureus

被引：0
作者：
Baldassarri L. [2 ]
Bertuccini L. [2 ]
Ammendolia M.G. [2 ]
Arciola C.R. [1 ]
Montanaro L. [1 ]
机构：
[1] Laboratorio di Biocompatibilità dei Materiali da Impianto, Istituti Ortopedici Rizzoli, 40136 Bologna
[2] Laboratorio di Ultrastrutture, Istituto Superiore di Sanità, 00161 Rome
来源：
European Journal of Clinical Microbiology and Infectious Diseases | 2001年 / 20卷 / 5期
关键词：
Glucose; Iron; Carbohydrate; Growth Condition; Staphylococcus Aureus;
D O I：
10.1007/PL00011274
中图分类号：
学科分类号：
摘要：
The aim of this study was to examine the effect of growth conditions on slime production by Staphylococcus aureus clinical isolates. The addition of glucose to the medium enhanced slime production in the majority of Staphylococcus aureus isolates cultured from infections associated with orthopaedic prostheses. Iron limitation also stimulated this ability even in the absence of the additional carbohydrate source. Staphylococcus aureus isolates were classified as Group 1 [strains producing slime only in trypticase soy broth supplemented with 1% glucose (TSBG) or in iron-limited trypticase soy broth (TSB/Fe-)]; Group 2 (slime + only in TSB/Fe-); or Group 3 (slime + only in TSBG). Seven repeatedly slime-negative strains were stimulated to produce slime by subpassaging in iron-limited medium. Low iron levels, usually found in vivo, could stimulate slime production by Staphylococcus aureus and support chronic infections associated with orthopaedic prostheses.
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页码：343 / 345
页数：2
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