Aspergillus osteomyelitis of the proximal humerus: a case report

被引：0
作者：
Gregory L. Hall
Esperanza Villanueva-Siles
Ross M. Borzykowski
Konrad I. Gruson
Howard D. Dorfman
David S. Geller
机构：
[1] The Albert Einstein College of Medicine,Department of Surgical Pathology
[2] Montefiore Medical Center and The Children’s Hospital at Montefiore,Department of Radiology
[3] Montefiore Medical Center and The Children’s Hospital at Montefiore,Department of Orthopaedic Surgery
[4] Montefiore Medical Center and The Children’s Hospital at Montefiore,Montefiore Medical Center
[5] Green Medical Arts Pavilion,undefined
来源：
Skeletal Radiology | 2012年 / 41卷
关键词：
Aspergillosis; Osteomyelitis; Antifungal pharmacology;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Aspergillus osteomyelitis is an extremely rare manifestation of invasive aspergillosis. Generally, patients in states of significant immune deficiency are very susceptible to invasive aspergillosis. We report a case of Aspergillus osteomyelitis of the proximal humerus in an immunocompetent patient that required aggressive oral antifungal therapy, surgical debridement, and placement of an antifungal-impregnated cement spacer. Subsequently, her shoulder was reconstructed using a reverse total shoulder prosthesis The clinical course, radiographic findings, histology, and management rationale are presented.
引用
收藏
页码：1021 / 1025
页数：4
相关论文
共 55 条
  • [1] Bennett J(1842)On the parasitic vegetable structures found growing in living granulocyte animals Trans R Soc Edinburgh 15 277-279
  • [2] Schaffner A(1982)Selective protection against conidia by mononuclear and against mycelia by polymorphonuclear phagocytes in resistance to Aspergillus. Observations on these two lines of defense in vivo and in vitro with human and mouse phagocytes J Clin Investigat 69 617-631
  • [3] Douglas H(1993)Impairment of neutrophil antifungal activity against hyphae of Aspergillus fumigatus in children infected with human immunodeficiency virus J Infect Dis 167 905-911
  • [4] Braude A(1983)Invasive aspergillosis in renal transplant recipients: correlation with corticosteroid therapy J Infect Dis 148 230-238
  • [5] Roilides E(1990)Antifungal and surgical treatment of invasive aspergillosis: review of 2,121 published cases Rev Infect Dis 12 1147-1201
  • [6] Holmes A(2005)Voriconazole for invasive bone aspergillosis: a worldwide experience of 20 cases Clin Infect Dis Official Publication Infect Dis Soc Am 40 1141-1147
  • [7] Blake C(2009)Aspergillus osteomyelitis: review of 12 cases identified by the prospective antifungal therapy alliance registry Diagn Microbiol Infect Dis 63 384-387
  • [8] Pizzo PA(1997)Fine-needle aspiration biopsy in fungal infections Diagn Cytopathol 16 31-34
  • [9] Walsh TJ(1985)Aspergillus osteomyelitis. Report of a case and review of the literature Diagn Microbiol Infect Dis 3 515-519
  • [10] Gustafson TL(1995)Extra-pulmonary manifestations of invasive aspergillosis Ann Med Interne 146 96-101
123456