Bacterial colonization factors control specificity and stability of the gut microbiota

被引:0
|
作者
S. Melanie Lee
Gregory P. Donaldson
Zbigniew Mikulski
Silva Boyajian
Klaus Ley
Sarkis K. Mazmanian
机构
[1] California Institute of Technology,Division of Biology and Biological Engineering
[2] La Jolla Institute for Allergy and Immunology,Division of Inflammation Biology
来源
Nature | 2013年 / 501卷
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摘要
Germ-free mice mono-associated with a single species of Bacteroides are found to be resistant to further colonization by the same, but not different, species; a unique class of polysaccharide utilization loci that is required for the penetration of the colonic mucus and colonization of the crypt channel niche is discovered that explains this observed species-specific saturable colonization.
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页码:426 / 429
页数:3
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