Abnormal DNA methylation within HPA-axis genes years after paediatric critical illness

[1] Jacobs A(2020)Dynamics and prognostic value of the hypothalamus–pituitary–adrenal axis responses to pediatric critical illness and association with corticosteroid treatment: a prospective observational study Intensive Care Med 46 70-81

[2] Derese I(2019)Non-thyroidal illness syndrome in critically ill children: prognostic value and impact of nutritional management Thyroid 29 480-492

[3] Vander Perre S(2011)Effect of intensive insulin therapy on the somatotropic axis of critically ill children J Clin Endocrinol Metab 96 2558-2566

[4] Wouters PJ(2019)The GH axis in relation to accepting an early macronutrient deficit and outcome of critically ill patients J Clin Endocrinol Metab 104 5507-5518

[5] Verbruggen S(2005)Activity of the growth hormone/insulin-like growth factor-I axis in critically ill children J Pediatr Endocrinol Metab 18 363-372

[6] Billen J(2019)Adrenal function and dysfunction in critically ill patients Nat Rev Endocrinol 15 417-427

[7] Jacobs A(2023)The hypothalamus-pituitary-adrenocortical response to critical illness: a concept in need of revision Endocr Rev 44 1096-1106

[8] Derese I(2009)Serum free cortisol index, free cortisol, and total cortisol in critically ill children Intensive Care Med 35 1281-1285

[9] Vander Perre S(2014)Evaluation of endocrine function in children admitted to pediatric intensive care unit Pediatr Int 56 349-353

[10] van Puffelen E(2018)Adrenocortical function during prolonged critical illness and beyond: a prospective observational study Intensive Care Med 44 1720-1729

[1] Jacobs A(2020)Dynamics and prognostic value of the hypothalamus–pituitary–adrenal axis responses to pediatric critical illness and association with corticosteroid treatment: a prospective observational study Intensive Care Med 46 70-81

[2] Derese I(2019)Non-thyroidal illness syndrome in critically ill children: prognostic value and impact of nutritional management Thyroid 29 480-492

[3] Vander Perre S(2011)Effect of intensive insulin therapy on the somatotropic axis of critically ill children J Clin Endocrinol Metab 96 2558-2566

[4] Wouters PJ(2019)The GH axis in relation to accepting an early macronutrient deficit and outcome of critically ill patients J Clin Endocrinol Metab 104 5507-5518

[5] Verbruggen S(2005)Activity of the growth hormone/insulin-like growth factor-I axis in critically ill children J Pediatr Endocrinol Metab 18 363-372

[6] Billen J(2019)Adrenal function and dysfunction in critically ill patients Nat Rev Endocrinol 15 417-427

[7] Jacobs A(2023)The hypothalamus-pituitary-adrenocortical response to critical illness: a concept in need of revision Endocr Rev 44 1096-1106

[8] Derese I(2009)Serum free cortisol index, free cortisol, and total cortisol in critically ill children Intensive Care Med 35 1281-1285

[9] Vander Perre S(2014)Evaluation of endocrine function in children admitted to pediatric intensive care unit Pediatr Int 56 349-353

[10] van Puffelen E(2018)Adrenocortical function during prolonged critical illness and beyond: a prospective observational study Intensive Care Med 44 1720-1729