Novel titanocene anti-cancer drugs and their effect on apoptosis and the apoptotic pathway in prostate cancer cells

被引：0
作者：
K. O'Connor
C. Gill
M. Tacke
F.-J. K. Rehmann
K. Strohfeldt
N. Sweeney
J. M. Fitzpatrick
R. W. G. Watson
机构：
[1] Mater Misericordiae University Hospital,UCD School of Medicine and Medical Sciences
[2] University College Dublin,UCD School of Chemistry and Chemical Biology
[3] University College Dublin and Dublin Molecular Medicine Centre,Conway Institute
[4] Conway Institute,UCD School of Medicine and Medical Sciences
[5] University College Dublin,undefined
来源：
Apoptosis | 2006年 / 11卷
关键词：
Apoptosis; Cell cycle; Mitochondria; Prostate cancer; Titanocene;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Advanced prostate cancer is not curable by current treatment strategies indicating a significant need for new chemotherapeutic options. Highly substituted ansa-titanocene compounds have shown promising cytotoxic activity in a range of cancers. The objectives of this study are to examine the effects of these titanocene compounds on prostate cancer cells.
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页码：1205 / 1214
页数：9
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