Growth hormone treatment in non-growth hormone-deficient short children

被引：0
作者：
S. Loche
M. R. Casini
G. M. Ubertini
M. Cappa
机构：
[1] Ospedale Regionale per le Microcitemie,Division of Pediatric Endocrinology
[2] Ospedale Bambino Gesù IRCCS,Department of Pediatrics, Unit of Endocrinology and Diabetes
[3] Ospedale Regionale per le Microcitemie,Servizio di Endocrinologia Pediatrica
来源：
Journal of Endocrinological Investigation | 2005年 / 28卷
关键词：
Children; growth hormone; puberty; short stature;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The unlimited availability of GH obtained by recombinant DNA technology has allowed optimization of treatment in GH-deficient (GHD) children. At the same time it has prompted a number of studiesin conditions not characterized by GHD such as Turner syndrome, intrauterine growth retardation, chronic renal failure and other chromosomal and genetic abnormalities associated with short stature. Several controlled and uncontrolled studies have now reported the adult height of patients with short stature and normal GH secretion. Critical reviewing of the data shows that some short non-GHD children may benefit from a prolonged treatment with GH. However, further studies are needed in order to be able to identify the subjects for whom treatment is really beneficial.
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页码：193 / 198
页数：5
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