Drug-Related DeathsAn Analysis of the Italian Spontaneous Reporting Database

被引:0
|
作者
Roberto Leone
Laura Sottosanti
Maria Luisa Iorio
Carmela Santuccio
Anita Conforti
Vilma Sabatini
Ugo Moretti
Mauro Venegoni
机构
[1] University of Verona,Clinical Pharmacology Unit, Reference Centre for Education and Communication within the WHO Programme for International Drug Monitoring
[2] Agenzia Italiana del Farmaco,undefined
[3] Clinical Pharmacology Unit,undefined
[4] Policlinico G.B. Rossi,undefined
来源
Drug Safety | 2008年 / 31卷
关键词
Nimesulide; Ticlopidine; Thrombotic Thrombocytopenic Purpura; Anaphylactic Shock; Reporting Odds Ratio;
D O I
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中图分类号
学科分类号
摘要
Background: Adverse drug reactions (ADRs) represent a major public health concern, with death as the ultimate adverse drug outcome. Despite the relevance of this, the frequency of fatal ADRs (FADRs) is to a large extent unknown. Although spontaneous reporting data cannot give an exact estimate of the magnitude of drug-related mortality, it may highlight the importance and large dimensions of this public health problem.
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页码:703 / 713
页数:10
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