Identification of Apigenin Metabolites in Rat Liver Perfusate by Column Switching High Performance Liquid Chromatography/Electrospray Ionization Mass Spectrometry

被引:0
|
作者
Jean-Philippe Basly
Anséline Gradolatto
Caroline Teyssier
Naric Chantal Canivenc-Lavier
机构
[1] UPRES EA 1085 “Biomolécules et Cibles Cellulaires Tumorales”,
[2] UFR de Pharmacie,undefined
[3] F-87025 Limoges,undefined
[4] France,undefined
[5] UMR 938 “Toxicologie Alimentaire”,undefined
[6] INRA,undefined
[7] BP 86510,undefined
[8] F-21065 Dijon,undefined
[9] France,undefined
来源
Monatshefte für Chemie / Chemical Monthly | 2003年 / 134卷
关键词
Keywords. Endocrine disrupters; Apigenin; Metabolites; HPLC; Column switching; Electrospray.;
D O I
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中图分类号
学科分类号
摘要
 A selective column switching high performance liquid chromatographic method has been used for the simultaneous determination of apigenin and metabolites in rat liver perfusate. This new method clearly separated apigenin and the metabolites with high resolution. The structures of metabolites were proposed based on selective ion recording and full scan analysis by electrospray ionization mass spectrometry.
引用
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页码:355 / 359
页数:4
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