The tumor microenvironment as driver of stemness and therapeutic resistance in breast cancer: New challenges and therapeutic opportunities

被引:0
作者
Umar Mehraj
Rais A. Ganai
Muzafar A. Macha
Abid Hamid
Mohammed A. Zargar
Ajaz A. Bhat
Mohd Wasim Nasser
Mohammad Haris
Surinder K. Batra
Bader Alshehri
Raid Saleem Al-Baradie
Manzoor A. Mir
Nissar Ahmad Wani
机构
[1] University of Kashmir,Department of Bioresources
[2] Islamic University of Science & Technology ,Watson
[3] Central University of Kashmir,Crick Centre for Molecular Medicine
[4] Sidra Medicine,Department of Biotechnology, School of Life Sciences
[5] University of Nebraska Medical Center,Translational Medicine, Research Branch
[6] Qatar University,Department of Biochemistry and Molecular Biology
[7] Eppley Institute for Research in Cancer and Allied Diseases,Laboratory of Animal Research
[8] University of Nebraska,Buffett Cancer Center
[9] University of Nebraska Medical Center,Department of Medical Laboratory Sciences, College of Applied Medical Sciences
[10] Majmaah University,undefined
来源
Cellular Oncology | 2021年 / 44卷
关键词
Breast cancer; Tumor microenvironment; Targeted therapeutics; Cancer-associated fibroblasts; Tumor-associated macrophages; Immunotherapy; Cancer stemness;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1209 / 1229
页数:20
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[1]  
Gluz O(2009)Liedtke C, Gottschalk N, Triple-negative breast cancer—current status and future directions Ann Oncol 20 1913-1927
[2]  
Maley CC(2017)Classifying the evolutionary and ecological features of neoplasms Nat. Rev. Cancer 17 605-619
[3]  
Aktipis A(2008)Differential gene expression profile in breast cancer-derived stromal fibroblasts Breast Cancer Res. Treat. 110 273-281
[4]  
Graham TA(2017)Study of the tumor microenvironment during breast cancer progression Cancer Cell Int. 17 123-597
[5]  
Sottoriva A(2018)Cancer-associated fibroblasts as key regulators of the breast cancer tumor microenvironment Cancer Metastasis Rev. 37 577-572
[6]  
Boddy AM(2016)Iravani M, Robertson D, Fearns A, Gao Q, Klingbeil P, Tumour cell-derived Wnt7a recruits and activates fibroblasts to promote tumour aggressiveness Nat. Commun. 7 10305-12
[7]  
Janiszewska M(2020)Cancer associated fibroblasts: Role in breast cancer and potential as therapeutic targets Expert Opin. Ther. Targets 24 559-67
[8]  
Silva AS(2013)Breast cancer-associated fibroblasts induce epithelial-to-mesenchymal transition in breast cancer cells Endocr Relat Cancer 20 1-9155
[9]  
Gerlinger M(2010)Matrix metalloproteinases: regulators ofthe tumor microenvironment Cell 141 52-2033
[10]  
Yuan Y(2009)Fibroblast hepatocyte growth factor promotes invasion of human mammary ductal carcinoma in situ Can. Res. 69 9148-795