Deep learning-based rapid generation of broadly reactive antibodies against SARS-CoV-2 and its Omicron variant

被引：0
|
作者：
Hantao Lou
Jianqing Zheng
Xiaohang (Leo) Fang
Zhu Liang
Meihan Zhang
Yu Chen
Chunmei Wang
Xuetao Cao
机构：
[1] Nankai University,Frontier Research Center for Cell Response, Nankai
[2] University of Oxford,Oxford International Advanced Research Institute, College of Life Sciences
[3] University of Oxford,Ludwig Institute for Cancer Research
[4] University of Oxford,The Kennedy Institute of Rheumatology
[5] University of Oxford,Big Data Institute
[6] University of Oxford,Department of Engineering Science
[7] University of Oxford,Target Discovery Institute, Centre for Medicines Discovery, Nuffield Department of Medicine
[8] Chinese Academy of Medical Sciences,Chinese Academy for Medical Sciences Oxford Institute, Nuffield Department of Medicine
来源：
Cell Research | 2023年 / 33卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：80 / 82
页数：2
相关论文
共 50 条
  • [1] Deep learning-based rapid generation of broadly reactive antibodies against SARS-CoV-2 and its Omicron variant
    Lou, Hantao
    Zheng, Jianqing
    Fang, Xiaohang
    Liang, Zhu
    Zhang, Meihan
    Chen, Yu
    Wang, Chunmei
    Cao, Xuetao
    CELL RESEARCH, 2023, 33 (01) : 80 - 82
  • [2] Broadly neutralizing human antibodies against Omicron subvariants of SARS-CoV-2
    Chiang, Hsiao-Ling
    Liang, Kang-Hao
    Lu, Ruei-Min
    Kuo, Ting-Wen
    Lin, Yi-Ling
    Wu, Han-Chung
    JOURNAL OF BIOMEDICAL SCIENCE, 2023, 30 (01)
  • [3] Broadly neutralizing human antibodies against Omicron subvariants of SARS-CoV-2
    Hsiao-Ling Chiang
    Kang-Hao Liang
    Ruei-Min Lu
    Ting-Wen Kuo
    Yi‑Ling Lin
    Han-Chung Wu
    Journal of Biomedical Science, 30
  • [4] Rapid decline in vaccine-boosted neutralizing antibodies against SARS-CoV-2 Omicron variant
    Lyke, Kirsten E.
    Atmar, Robert L.
    Islas, Clara Dominguez
    Posavad, Christine M.
    Szydlo, Daniel
    Chourdhury, Rahul Paul
    Deming, Meagan E.
    Eaton, Amanda
    Jackson, Lisa A.
    Branche, Angela R.
    Sahly, Hana M. El
    Rostad, Christina A.
    Martin, Judith M.
    Johnston, Christine
    Rupp, Richard E.
    Mulligan, Mark J.
    Brady, Rebecca C.
    Frenck, Robert W., Jr.
    Backer, Martin
    Kottkamp, Angelica C.
    Babu, Tara M.
    Rajakumar, Kumaravel
    Edupuganti, Srilatha
    Dobrzynski, David
    Coler, Rhea N.
    Archer, Janet I.
    Crandon, Sonja
    Zemanek, Jillian A.
    Brown, Elizabeth R.
    Neuzil, Kathleen M.
    Stephens, David S.
    Post, Diane J.
    Nayak, Seema U.
    Suthar, Mehul S.
    Roberts, Paul C.
    Beigel, John H.
    Montefiori, David C.
    DMID Std Grp
    CELL REPORTS MEDICINE, 2022, 3 (07)
  • [5] Rapid development of an updated mRNA vaccine against the SARS-CoV-2 Omicron variant
    Na-Na Zhang
    Rong-Rong Zhang
    Yi-Fei Zhang
    Kai Ji
    Xiao-Chuan Xiong
    Qian-Shan Qin
    Peng Gao
    Xi-Shan Lu
    Hang-Yu Zhou
    Hai-Feng Song
    Bo Ying
    Cheng-Feng Qin
    Cell Research, 2022, 32 : 401 - 403
  • [6] Rapid development of an updated mRNA vaccine against the SARS-CoV-2 Omicron variant
    Zhang, Na-Na
    Zhang, Rong-Rong
    Zhang, Yi-Fei
    Ji, Kai
    Xiong, Xiao-Chuan
    Qin, Qian-Shan
    Gao, Peng
    Lu, Xi-Shan
    Zhou, Hang-Yu
    Song, Hai-Feng
    Ying, Bo
    Qin, Cheng-Feng
    CELL RESEARCH, 2022, 32 (04) : 401 - 403
  • [7] Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
    Cameroni, Elisabetta
    Bowen, John E.
    Rosen, Laura E.
    Saliba, Christian
    Zepeda, Samantha K.
    Culap, Katja
    Pinto, Dora
    VanBlargan, Laura A.
    De Marco, Anna
    di Iulio, Julia
    Zatta, Fabrizia
    Kaiser, Hannah
    Noack, Julia
    Farhat, Nisar
    Czudnochowski, Nadine
    Havenar-Daughton, Colin
    Sprouse, Kaitlin R.
    Dillen, Josh R.
    Powell, Abigail E.
    Chen, Alex
    Maher, Cyrus
    Yin, Li
    Sun, David
    Soriaga, Leah
    Bassi, Jessica
    Silacci-Fregni, Chiara
    Gustafsson, Claes
    Franko, Nicholas M.
    Logue, Jenni
    Iqbal, Najeeha Talat
    Mazzitelli, Ignacio
    Geffner, Jorge
    Grifantini, Renata
    Chu, Helen
    Gori, Andrea
    Riva, Agostino
    Giannini, Olivier
    Ceschi, Alessandro
    Ferrari, Paolo
    Cippa, Pietro E.
    Franzetti-Pellanda, Alessandra
    Garzoni, Christian
    Halfmann, Peter J.
    Kawaoka, Yoshihiro
    Hebner, Christy
    Purcell, Lisa A.
    Piccoli, Luca
    Pizzuto, Matteo Samuele
    Walls, Alexandra C.
    Diamond, Michael S.
    NATURE, 2022, 602 (7898) : 664 - +
  • [8] Broadly neutralizing antibodies overcome SARS-CoV-2 Omicron antigenic shift
    Elisabetta Cameroni
    John E. Bowen
    Laura E. Rosen
    Christian Saliba
    Samantha K. Zepeda
    Katja Culap
    Dora Pinto
    Laura A. VanBlargan
    Anna De Marco
    Julia di Iulio
    Fabrizia Zatta
    Hannah Kaiser
    Julia Noack
    Nisar Farhat
    Nadine Czudnochowski
    Colin Havenar-Daughton
    Kaitlin R. Sprouse
    Josh R. Dillen
    Abigail E. Powell
    Alex Chen
    Cyrus Maher
    Li Yin
    David Sun
    Leah Soriaga
    Jessica Bassi
    Chiara Silacci-Fregni
    Claes Gustafsson
    Nicholas M. Franko
    Jenni Logue
    Najeeha Talat Iqbal
    Ignacio Mazzitelli
    Jorge Geffner
    Renata Grifantini
    Helen Chu
    Andrea Gori
    Agostino Riva
    Olivier Giannini
    Alessandro Ceschi
    Paolo Ferrari
    Pietro E. Cippà
    Alessandra Franzetti-Pellanda
    Christian Garzoni
    Peter J. Halfmann
    Yoshihiro Kawaoka
    Christy Hebner
    Lisa A. Purcell
    Luca Piccoli
    Matteo Samuele Pizzuto
    Alexandra C. Walls
    Michael S. Diamond
    Nature, 2022, 602 : 664 - 670
  • [9] Broadly neutralizing antibodies against Omicron-included SARS-CoV-2 variants induced by vaccination
    Chi, Xiangyang
    Guo, Yingying
    Zhang, Guanying
    Sun, Hancong
    Zhang, Jun
    Li, Min
    Chen, Zhengshan
    Han, Jin
    Zhang, Yuanyuan
    Zhang, Xinghai
    Fan, Pengfei
    Zhang, Zhe
    Wang, Busen
    Zai, Xiaodong
    Han, Xuelian
    Hao, Meng
    Fang, Ting
    Xu, Jinghan
    Wu, Shipo
    Chen, Yi
    Fang, Yingying
    Dong, Yunzhu
    Sun, Bingjie
    Zhang, Jinlong
    Li, Jianmin
    Zhao, Guangyu
    Yu, Changming
    Zhou, Qiang
    Chen, Wei
    SIGNAL TRANSDUCTION AND TARGETED THERAPY, 2022, 7 (01)
  • [10] Broadly neutralizing antibodies against Omicron-included SARS-CoV-2 variants induced by vaccination
    Xiangyang Chi
    Yingying Guo
    Guanying Zhang
    Hancong Sun
    Jun Zhang
    Min Li
    Zhengshan Chen
    Jin Han
    Yuanyuan Zhang
    Xinghai Zhang
    Pengfei Fan
    Zhe Zhang
    Busen Wang
    Xiaodong Zai
    Xuelian Han
    Meng Hao
    Ting Fang
    Jinghan Xu
    Shipo Wu
    Yi Chen
    Yingying Fang
    Yunzhu Dong
    Bingjie Sun
    Jinlong Zhang
    Jianmin Li
    Guangyu Zhao
    Changming Yu
    Qiang Zhou
    Wei Chen
    Signal Transduction and Targeted Therapy, 7
12345