Induction of remission following a single dose of rituximab alone in a patient with minimal change nephrotic syndrome

被引：0
作者：
Nobuyuki Amemiya
Takashi Takei
Chiari Kojima
Hirohiko Nokiba
Mitsuyo Itabashi
Kosaku Nitta
机构：
[1] Tokyo Women’s Medical University,Department of Medicine, Kidney Center
来源：
Clinical and Experimental Nephrology | 2011年 / 15卷
关键词：
Frequently relapsing minimal change nephrotic syndrome; Rituximab; Monotherapy;
D O I：
暂无
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学科分类号：
摘要：
Treatment with a single dose of rituximab alone induced remission in a patient with relapsed minimal change nephrotic syndrome (MCNS). A 27-year-old man was given corticosteroid (prednisolone; PSL) and cyclosporine (CyA) therapy combined with rituximab for his fifth relapse in 2008. Thereafter, complete remission was achieved and maintained despite eventual discontinuation of the PSL and CyA. In 2010, we treated his sixth relapse with a single dose of rituximab. Complete remission was obtained 32 days later. This is the first report of rituximab monotherapy in the treatment of MCNS.
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页码：933 / 936
页数：3
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