Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

被引:0
|
作者
Fumiji Saito
Kouyuki Hirayasu
Takeshi Satoh
Christian W. Wang
John Lusingu
Takao Arimori
Kyoko Shida
Nirianne Marie Q. Palacpac
Sawako Itagaki
Shiroh Iwanaga
Eizo Takashima
Takafumi Tsuboi
Masako Kohyama
Tadahiro Suenaga
Marco Colonna
Junichi Takagi
Thomas Lavstsen
Toshihiro Horii
Hisashi Arase
机构
[1] Research Institute for Microbial Diseases,Department of Immunochemistry
[2] Osaka University,Department of Immunology and Microbiology
[3] Suita,Department of Infectious Diseases
[4] Laboratory of Immunochemistry,Department of Molecular Protozoology
[5] WPI Immunology Frontier Research Centre,Department of Medical Zoology
[6] Osaka University,Department of Environmental Parasitology
[7] Suita,Division of Malaria Research
[8] Centre for Medical Parasitology,Department of Pathology and Immunology
[9] University of Copenhagen,Division of Systems Immunology, Institute of Medical Science
[10] Copenhagen University Hospital (Rigshospitalet),undefined
[11] National Institute for Medical Research,undefined
[12] Tanga Research Centre,undefined
[13] Laboratory of Protein Synthesis and Expression,undefined
[14] Institute for Protein Research,undefined
[15] Osaka University,undefined
[16] Research Institute for Microbial Diseases,undefined
[17] Osaka University,undefined
[18] School of Medicine,undefined
[19] Mie University,undefined
[20] Tokyo Medical and Dental University,undefined
[21] Proteo-Science Centre,undefined
[22] Ehime University,undefined
[23] Washington University School of Medicine,undefined
[24] The University of Tokyo,undefined
来源
Nature | 2017年 / 552卷
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摘要
Proteins expressed on the surfaces of erythrocytes infected with Plasmodium falciparum help the parasite to evade the host immune system by acting as ligands for immune inhibitory receptors and thereby downregulating the immune response.
引用
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页码:101 / 105
页数:4
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