Immune evasion of Plasmodium falciparum by RIFIN via inhibitory receptors

被引:0
|
作者
Fumiji Saito
Kouyuki Hirayasu
Takeshi Satoh
Christian W. Wang
John Lusingu
Takao Arimori
Kyoko Shida
Nirianne Marie Q. Palacpac
Sawako Itagaki
Shiroh Iwanaga
Eizo Takashima
Takafumi Tsuboi
Masako Kohyama
Tadahiro Suenaga
Marco Colonna
Junichi Takagi
Thomas Lavstsen
Toshihiro Horii
Hisashi Arase
机构
[1] Research Institute for Microbial Diseases,Department of Immunochemistry
[2] Osaka University,Department of Immunology and Microbiology
[3] Suita,Department of Infectious Diseases
[4] Laboratory of Immunochemistry,Department of Molecular Protozoology
[5] WPI Immunology Frontier Research Centre,Department of Medical Zoology
[6] Osaka University,Department of Environmental Parasitology
[7] Suita,Division of Malaria Research
[8] Centre for Medical Parasitology,Department of Pathology and Immunology
[9] University of Copenhagen,Division of Systems Immunology, Institute of Medical Science
[10] Copenhagen University Hospital (Rigshospitalet),undefined
[11] National Institute for Medical Research,undefined
[12] Tanga Research Centre,undefined
[13] Laboratory of Protein Synthesis and Expression,undefined
[14] Institute for Protein Research,undefined
[15] Osaka University,undefined
[16] Research Institute for Microbial Diseases,undefined
[17] Osaka University,undefined
[18] School of Medicine,undefined
[19] Mie University,undefined
[20] Tokyo Medical and Dental University,undefined
[21] Proteo-Science Centre,undefined
[22] Ehime University,undefined
[23] Washington University School of Medicine,undefined
[24] The University of Tokyo,undefined
来源
Nature | 2017年 / 552卷
关键词
D O I
暂无
中图分类号
学科分类号
摘要
Proteins expressed on the surfaces of erythrocytes infected with Plasmodium falciparum help the parasite to evade the host immune system by acting as ligands for immune inhibitory receptors and thereby downregulating the immune response.
引用
收藏
页码:101 / 105
页数:4
相关论文
共 50 条
  • [31] IMMUNE EVASION BY BABESIA-BOVIS AND PLASMODIUM-FALCIPARUM - CLIFF-DWELLERS OF THE PARASITE WORLD
    ALLRED, DR
    PARASITOLOGY TODAY, 1995, 11 (03): : 100 - 105
  • [32] Immune evasion runs in the family: two surface protein families of Plasmodium falciparum-infected erythrocytes
    Chamberlain, Samuel G.
    Iwanaga, Shiroh
    Higgins, Matthew K.
    CURRENT OPINION IN MICROBIOLOGY, 2025, 85
  • [33] THE INHIBITORY EFFECT OF HUMAN IMMUNE SERA UPON THE INVITRO DEVELOPMENT OF PLASMODIUM-FALCIPARUM
    GOLENSER, J
    MILLER, J
    AVRAHAM, H
    SPIRA, DT
    TROPICAL AND GEOGRAPHICAL MEDICINE, 1983, 35 (01): : 15 - 20
  • [34] RSpred, a set of Hidden Markov Models to detect and classify the RIFIN and STEVOR proteins of Plasmodium falciparum
    Nicolas Joannin
    Yvonne Kallberg
    Mats Wahlgren
    Bengt Persson
    BMC Genomics, 12
  • [35] Revisiting the Plasmodium falciparum RIFIN family: from comparative genomics to 3D-model prediction
    Emanuele Bultrini
    Kevin Brick
    Srayanta Mukherjee
    Yang Zhang
    Francesco Silvestrini
    Pietro Alano
    Elisabetta Pizzi
    BMC Genomics, 10
  • [36] The immune response to Plasmodium falciparum malaria
    Malaguarnera, L
    Musumeci, S
    LANCET INFECTIOUS DISEASES, 2002, 2 (08) : 472 - 478
  • [37] Variant proteins of the Plasmodium falciparum RIFIN family show distinct subcellular localization and developmental expression patterns
    Petter, Michaela
    Haeggstroem, Malin
    Khattab, Ayman
    Fernandez, Victor
    Klinkert, Mo-Quen
    Wahlgren, Mats
    MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 2007, 156 (01) : 51 - 61
  • [38] Antibodies to rifin:: A component of naturally acquired responses to Plasmodium falciparum variant surface antigens on infected erythrocytes
    Abdel-Latif, MS
    Cabrera, G
    Köhler, C
    Kremsner, PG
    Luty, AJF
    AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2004, 71 (02) : 179 - 186
  • [39] PfEMP1: An antigen that plays a key role in the pathogenicity and immune evasion of the malaria parasite Plasmodium falciparum
    Pasternak, Noa D.
    Dzikowski, Ron
    INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 2009, 41 (07) : 1463 - 1466
  • [40] N-terminal region of Plasmodium falciparum circumsporozoite protein mediates immune evasion by hijacking a complement inhibitor
    Khattab, A.
    Riva, R.
    Kyrklund, M.
    Turunen, O.
    Meri, S.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2019, 49 : 173 - 173